E-Articles - Computers and Technology

Computer and technology products continue to improve, and color printers are no different. If you liked the printer your friend bought last

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

week, just wait. You'll be able to get one better and cheaper next week.

So, if you're in the market for a new home or small office printer

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

what should you get, ink-jet or laser? My short answer - laser. Let me explain.

When black ink-jet printers first came out you had to pay

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

omewhere in the neighborhood of $500. You could get a replacement ink cartridge for 20 bucks and you're good to go. Or, you could buy an in

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

refill kit and refill your cartridge for a fraction of the cost of a new cartridge. Well, those days are long gone. Now you pay twenty buc

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s for the printer and $500 for the ink! Well, not quite, but it seems that way.

I've worked on printers with a single color cartridge and w

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

th one cartridge for each of the three standard colors and either way, you end up paying a lot for ink. So what do a lot of people do to sav

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

money on ink? They use their printer as little as possible. While this may seem like a reasonable solution it creates another problem; the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ink dries up. Then when you go to print it's all streaky because the ink has dried up and clogged the microscopic jets. So what to do now?

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

You run your printer through the cleaning process, which, unfortunately, USES A TON OF INK!

Here's the answer, buy ink cartridges on sale an

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

stock up. Oops, wrong answer. Ink cartridges have an expiration date and usually don't work after that date.

How about refilling? Most c

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

artridges today use some kind of “smart” technology that knows when it's empty and won't work when refilled - plus it can be a real mess.

Th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

reason most ink-jet printers are so inexpensive today is that printer manufactures use the same business model as cell phone companies, that

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is, give away the phone (printer) and make the profit by regularly selling minutes (cartridges). Add to that the natural trend of computer p

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

oducts getting cheaper and the fact that today's printers are really cheaply made (notice I didn't say “inexpensive,” I said “cheap”) and you

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ll see $29 ink-jet printers all the time.

But don't think you can just buy a new printer whenever your ink runs out, because most printers a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e sold with “starter” cartridges which are less than 50% full.

So, what about color laser printers? Color laser printers have been around f

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r quite a few years now, costing about ten grand and weighing 100 pounds when the first came out. Now you can get one for under $300 that we

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ghs less than 40 pounds. So obviously it costs more to purchase a laser printer than an ink-jet printer, BUT, the cost per page is much less

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

with laser and the hassle is greatly reduced as well.

So, for routine small office and home use these days, I recommend color laser printers

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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