E-Articles - Computers and Technology

As home computers become more advanced, and our uses for them become more complex, the need for higher performance and capacity hard drives increases. It is now possible to choo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

se hard drives with vastly different capacities and rotational speeds, making things more confusing for the consumer.

Thankfully for consumers the hard drive market is extremel

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

y competitive and the price at which a high capacity hard drive can be bought is quite astounding. Now that broadband internet is common place, with more and more people downloa

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ing music and movies, the need for high specification hard drives has never been greater.

When choosing a new hard drive it is important to consider What you use your computer

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

for. Those who just use their home pc for basic requirements such as word processing and surfing the internet will not need to spend as much on their hard drive as someone who m

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

y use music applications or lots of games. When buying a hard drive also try and anticipate any future requirements also.

Lets consider the following hard drive specifications:

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

1)Capacity

2)Rotational speed

3)Buffer size and transfer rates

In terms of capacity, hard drives can range from 30 - 300 GB. 40 GB hard drives are fairly standard these day

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s. If all you will be using your PC for is to run a few basic software applications and games then this will provide you with plenty of space. But as most people these days are

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

enerally also using their home computer to store lots of music, videos and photos, I would strongly recomend buying something between 60 - 120 GB capacity. With hard drives bein

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

g relatively cheap these days it is better to buy something that will continue to provide storage in the future, than go for a smaller option now and have to upgrade sooner.

Th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

second factor we really need to consider is the rotational speed of the hard drives. This has become a big selling point for manufacturers. The speed is measured in revolutions

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

per minute and you will find figures such as 5400RPM, 7200RPM, 10000RPM, 15000RPM quoted by the hard drive manufacturers. Hard drives work by reading information from rotating

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

magnetic platters as they rotate, hence the faster the rotating speed, the quicker the information is read. There is a down side to faster rotating speeds though, and that is we

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r and tear. The faster a hard drive spins the quicker it will wear out and it will also be more vulnerable to crashes. Rotational speed is really important, so if your going to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

be using your PC for music or gaming then you need to buy a 7200RPM drive. If its just for basic usage then a 5400RPM drive will suffice. Again as the price difference between 7

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

00RPM and 540RPM drives is minimal, you may consider opting for the faster speed as this will not need upgrading as soon.

The buffer size and transfer rates will not be of impo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rtance to many people, and only need to be considerd by people building dedicated games machines or for high end music applications. The buffer is used as a temporary store fo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r data and the larger the buffer size the better your pc will operate. It is possible to buy hard drives with a buffer size of 8MB. Its best to buy a drive with as large a buffe

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

as you can afford. The same is true for transfer rates, buy the drive with the highest transfer rate that you can afford.

This buyers guide should have covered all the points

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

you need to consider when purchasing your new hard drive, but if you want more information then plenty is avaiable on the internet. For further information please visit our site

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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