E-Articles - Computers and Technology

Blu-ray is capable of storing and playing movies in 1080p resolution. In many respects, 1080p resolution is called "True High-Definition"

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

or "Full High-Definition". A Blu-ray disc can store and play roughly around 5 to 6 hours of high-definition content (1080p resolution) and

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

around 24 hours of standard-definition content (480i or 480p resolution). With the capability of storing up to 50 gigabytes of data, you will be

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

able to watch an entire Blu-ray movie with crisp clarity.

But what exactly is 1080p resolution?
Well

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

, the number 1080 means that there are 1,080 lines of vertical resolution. Generally the larger number of vertical resolution lines, the sharper

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nd more detailed the image. The letter "p" stands for progressive scan. Progressive scan (a.k.a. non-interlaced) is a way to transmit, store, or

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

display moving images. The other method of transmitting, storing, or displaying moving images is called interlace. Interlace is represented by

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the letter "i" (1080i). Interlace was created to improve video quality without consuming more bandwidth. However, progression scan is superior t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the interlaced method because the progression scan method transmits, stores, or displaying moving images by processing all horizontal lines seque

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ntially each frame. While the interlace method processes every other line in one frame, then the rest of the lines in the next. This results in

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

educed horizontal resolution. While the interlace method isn't all bad, and the progressive scan method isn't prefect, when it comes to which pro

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

vides the best picture quality, progressive scan is the way to go.

HD DVD has the capability to store and play movies in 1

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

080p, so why is Blu-ray better?
The answer to that question requires one word, space. A HD DVD has greater limitations

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

than Blu-ray. HD DVD discs and Blu-ray discs come in two forms, single layered and dual layered. Please note that the higher the number of gigab

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ytes, the more data that can be stored. A single layered HD DVD disc has a maximum capacity of 15 gigabytes and a single layered Blu-ray disc has

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a maximum capacity of 25 gigabytes. When these two discs are dual layered, their maximum capacities are doubled, with a HD DVD at 30 gigabytes and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Blu-ray at 50. So, at most Blu-ray can handle 20 gigabytes of additional storage, and with a world that is constantly changing, that extra 20 gi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

gabytes can make a world of difference.

Blu-ray movies: In the highest definition ever!
Blu-ray movies

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

have the edge over HD DVD movies. Due to the lack of space, HD DVD will eventually fall further and further behind. On the contrary, Blu-ray wil

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

l reach its full potential, being able to store more of the finest details and stunning visuals. Blu-ray has reached the highest definition ever

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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