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The modern age is witnessing the emergence of several innovative communication technologies. ADSL is o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ne such invention. ADSL stands for Asymmetric Digital Subscriber Line, and it helps to convert existin

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

g telephone lines into access paths for multimedia and high-speed data communications. Today, ADSL has

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

enabled the transformation of existing public information networks from voice, text and low-resolutio

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n graphics to a powerful tool for transmitting multimedia and full-motion video. Not surprisingly, ADS

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

L has unleashed a big revolution in modern homes.

With ADSL, subscribers can now get up to 6 Mbps of

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

data in one direction, or about 832 kbps or more data in both directions. These rates of expansion ena

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ble the expansion of existing access capacity by a factor of about 50 or more. And that too, without t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

he need for new cabling. The ADSL circuit uses an ADSL modem on each end of the twisted-pair telephone

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

line. Furthermore, it creates three information channels to function -- a high-speed downstream chann

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

el, a medium-speed duplex channel, and a POTS (Plain Old Telephone Service) or an ISDN channel. Depend

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ing on the system, each of these channels can be further submultiplexed to form multiple lower-rate ch

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

annels. High-speed channels range from 1.5 to 6.1 Mbps, while the duplex rates range varies from 16 to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

832 kbps.

The coming years are about to witness a tremendous enhancement of the ADSL. This developme

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nt will primarily come about as telephone companies and other service providers enter new markets and

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

deliver information in several heavy formats like multimedia and video. Although communication experts

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

are of the opinion that the new broadband cabling will take decades to reach all prospective subscrib

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ers, there are chances that the process may succeed only when more and more subscribers are reached in

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

the initial first few years. ADSL will make these new markets viable for telecom companies and applic

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ation suppliers by taking television, videos, movies, corporate LANs, remote CD-ROMs and the Internet.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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