E-Articles - Relationships

The First Realm of Love – The Physical Realm

I love you. I Love the look of you. I have got to have you in my life. I can’t live without you. I am desperate for you. You are everything I have dreamed and more. I am aroused by you, and therefore I cannot live without you. You are perfect. I am yours and you are mine. You have no fault. I cannot think of any reason that our love will

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

not last. I want to own you, marry you, posses you. I give up my life for you. I am infatuated with you.

I know this is highly charged. I am blinded by this love. I will throw away my dreams, my passions and my ambitions just to be with you. I also know, as people have warned me, that this love, this passion, this fire is unsustainable, but I am blind. I am blinded by my emotion a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nd the chemistry that rushes through my veins. I have been warned, but my life was hell before I met you, and now it is heaven. Oh, even for just this one day, this love, this fire, this mindlessness, is worth it.

Don’t leave me. And please can you give up your job. Please don’t go out tonight, stay home with me. Why can’t you trust me? I love you. Where are you going tomorrow? Why

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

didn’t you call? Yes, ok, I can give up that friend. Why are you watching television tonight? Why are you going to the football with your friends? Ok, I won’t stay late at the office. Fine, I’ll change for you, just give me time.

The second realm of Love – My mind

I love you. I think like you. Our dreams are so similar. I believe what you believe and I think what you think. I kn

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ow we are right in our way of life. We are on common ground, we live to this code, and this code is ours. We agree, we like the same paintings, we like the same holidays. We are of the same mind, we are in love.

I have told people that they should be like you. They should be good and they should be happy. I have told brothers and friends and family what they should be doing and now

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

, I have met you, and you and there is no need, because we agree. We agree, the world should be as we dream it should be.

I am not interested in what others believe, because we know what is right. Right for us, right for our lives. We are together and we know the way to the future. This makes me so happy. I love you because we are right for each other, and we know what is best for

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

us. They warn us, that we are being closed minded, but I don’t care, this is about what we think, what we know is right for us. This is our life, our love. This is right for us.

The third realm of love – Emotion

I love you. I cry at the thought of you. I write these poems of love for you. Poems that express this romance, this beauty, this feeling so deep inside me. From the moment

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

I met you I knew I loved you. I felt it deep in my core. I am sad without you, I am angry if I can’t be with you. I feel good around you, you make me happy, I want you near me all the time because it makes me feel so good, I need you in my life.

You are my sun, my morning, my every breath. You are the dew on my skin and the sun in my heart. I breathe you, and these roses, this gif

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t, this meal, this wine, this touch on your shoulder, this sends shivers down my spine. I hold your photograph close to my heart and I celebrate you with happiness. I wait for your call.

I am sorry for my reaction when you came home late. I am sorry for being angry. I can’t help it. I feel so wonderful and I feel so vulnerable. I feel you when I walk. Oh my love, may this feeling,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

this romance last forever between us. I am sorry about those swings in my mood. They are totally unexplainable. Oh, my love, be mine forever.

The forth realm of love – The heart

I love you. Whether you come or go in my life, I love you. No matter whether you are well or sick, for better for worse, for richer or poorer, all the days of my life. I will love you. I will love you no m

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ater what happens. I will love you. I know I love you, you and I are in love. It is destiny, we are friends for life, I love you.

I want you to be happy my love. Yes, why don’t you travel and see the world. Why not more to Africa and work, I will always be here for you. I want the family to be happy. I care so much for you. I want to hold you close, keep you warm. I want your life

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to be wonderful, and even more wonderful because of me.

I am happy that you are moving on from me. Yes, we are close friends. We have achieved a wonderful depth to our love, so much so, that you feel like my sister, or brother or something. I want you to be happy, and our friendship is vital. We can work together, be friends together for ever.

I am a bit sorry that the romance wen

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t out of our relationship. That we are such wonderful friends is amazing, but I really hoped that we would stay passionate. We grew away from that passion we had when we first met. Maybe we should have spent more time playing. I love you always, my love and my friend, forever.

The Fifth realm of love – Devotion

I love you. Deep in my heart I have known that one day I would find y

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ou. I knew that there was a lover, somewhere, whose life mission, whose life passion and mine would weave together to create something magnificent on this earth. We are like two musicians whose life purpose apart is quadrupled in value together.

We will serve our mission in life together. You bring gifts and I bring gifts and with these together, our highest calling will be to shar

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e these with the world. I love you deeply, I celebrate all the four realms of love with you, and now, this, our purpose in life.

This is more than me, this is more than you, this is sacred, our purpose together. We can do what we love in life and share that journey together. Thank you for opening your heart and your life for me. We are bound together by more than a contract of inti

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

macy and love, we are bound by our commitment to something bigger than both of us. I devote my love to you, I know in this way we will give what we are born to give. My love is eternal, thank you.

The Sixth realm of love – Inspired

I love you. Oh stillness of the night, let my mind be calm, my soul be content, let my love become one with yours. We were two, we are one. We bind at

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

all levels, from the physical and romantic to the emotional and fantastic. But most of all, we bind in light.

I walk with you, no matter where you go. I sleep with you no matter what you know. I am with you, always, awake or asleep, this is my eternal love. More than a pledge, it is real. I know your breath, I know your heart. I am not away, I am in your thought, in your realm, we

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

are one, we are bound.

Know me my love and you will know you. Dive each day through the emotion and challenge and anytime you choose, you will find me. Choose love and I am here. It is one step beyond, yet more real than they know. Let me hold you without arms, let me touch you without sound, see me without eyes, I am you, we are one, in love.

The Seventh Realm – Unconditional lo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ve

I love you. Emptiness. I cannot know time. I love you. Emptiness. I cannot know space. You are not in form, although I know your love. You are not in sound although I hear your call. We are one soul, one love, one now.

Beyond the realms where voices speak, we are bound more strong than lovers who weep. We sit without mind, we sit in that time and we know each other. I know you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

when I see mountains so high. A lake so still. A wind so kind. I know you when nature reminds me, I am loved, I am loved, I am loved.

I look to the stars and there you are. I look to the moon, it’s not so far. I look into nothing, to the beauty of all, and there you are, not so far at all. Invisible one, I can see you in the beauty of the simplest world. Never so far. Never so far.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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