E-Articles - Relationships

How many headaches are too many? As I never really have or had a headache, I keep wondering if this i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s really our most infamous excuse for not having sex. The most important question in my mind, though,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is: do we really need to have an excuse for not having sex? What does one do to avoid such a conflic

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

t of interests that is so obviously important in a relationship? Why can’t we just go along? After al

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

l, in the beginning of the relationship, we were eager to please. Why the change of heart? Are our me

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

n to blame? Truly, why is that we need to have an excuse?

A joke for you: It's a beautiful warm spr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ing day and a man and his wife are at the zoo. She's wearing a cute, loose-fitting, pink spring dress

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

, sleeveless with straps. As they walk through the ape exhibit and pass in front of a very large gori

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lla, the gorilla goes ape.

He jumps up on the bars, holding on with one hand (and 2 feet), grunting

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

and pounding his chest with the free hand. He is obviously excited at the pretty lady in the wavy dre

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ss. The husband, noticing the excitement, suggests that his wife tease the poor fellow.

The husband

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

suggests she pucker her lips, wiggle her bottom, and play along. She does and Mr. Gorilla gets even m

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ore excited, making noises that would wake the dead. Then the husband suggests that she let one of he

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r straps fall, she does, and Mr. Gorilla is just about to tear the bars down. "Now try lifting your d

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ress up your thighs."

... this drives the gorilla absolutely crazy.

Then, quickly the husband grabs

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

his wife by the hair, rips open the door to the cage, slings her in with the gorilla and says, "Now,

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tell HIM you have a headache."

A Word of Advice Ladies: No more excuses, please. You are a sexual

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

being and should act like one. After all, we have desires too.

Gents: Though you may feel like doing

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

the same as the husband in our story, don’t. Have a heart to heart talk and let her know how importa

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nt this is to you. If she refuses to accommodate you, then think of an alternative that pleases both.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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