E-Articles - Relationships

I have been observing couples and their conversations recently and I have made an interesting discovery, one I am sure that applies to you and your partner. If it doe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

sn’t your relationship is truly one in a million. I haven’t given this tendency a name yet but hopefully by the end of this article I will have figured something out

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

that is reflective and insightful.

It goes something like this.

He: “About three weeks ago………”
She: “It was just last week.”
She: “That movie was at least

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

two hours long.”
He: “It was only an hour and a half.”

I could go on. Today there will be millions of conversations that will mimic this conversational tendency

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Two things; does it really matter in the end, no matter what is being discussed? And, what are the long-term consequences of this need to correct others in the munda

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ne and unimportant conversational details of life?

Well, in the end I don’t think that most of these mild corrections really matter. In the grand scheme of things wh

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

at difference does it really make whether the move was 90 or 120 minutes long? During a recent social dinner outing with another couple I decided to count. During

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

his two hour meal each partner corrected the other a total of 35 times. We are not talking about rocket science stuff here where the need for accuracy is critical. W

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e are talking about simple and often unimportant life details that in the end really don’t matter one way or the other.

I started thinking, why was this necessary? W

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

hy do people feel the need to correct their partner? Ego, the need to be right, control, an insane focus on what was correct? Or some other hidden psychological motiv

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

? Since I don’t have a degree in psychology I can’t answer that, but I can tell you as the recipient of these kind of relentless corrections during my life that I soo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

n arrived at the point that I wanted to be around my partner as little as possible.

I can hear some of you now, “Tim you are making a big deal out of nothing. It’s ju

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

st life’s trivia.” Maybe yes and maybe no. All I can tell you is how this persistent behavior makes me feel. Why contribute. Why talk. Why engage when sooner or l

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ater the need for correction from the other person will emerge.

As an interesting sidebar, I have also noticed that when a group of guys or gals get together this sam

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

conversational tendency isn’t followed. There is no need for her to correct one of her friends nor he one of his. It seems that this tends to only happen when two

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

spouses are sharing either in private or when they are among friends at a social gathering.

I am not an expert on anything. But I do know a little bit about a numbe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r of subjects and when my expertise (a simple point or detail) on one of these is corrected by someone with less knowledge on the subject that is being discussed, I d

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tend to get somewhat annoyed. Do I fight back? Make a stand? Do I let them have their way? Do I pick my battles? Do I just shut up and forget it? Do I suck it i

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

n and smile? Do I make a big deal of nothing?

I know I am not being much help here. All I can tell you is that over time this constant need to correct will take its

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

toll on the intimacy, respect, openness and vulnerability in the relationship. So, what do I call this tendency? Let’s call it the ‘Correction Syndrome’ – clever huh

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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