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    Women love to talk (just think of how long they talk on the telephone). Women like to help (j
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ust think of a typical "female" job: nurse, kindergarten teacher, geriatric nurse...). Combin
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    e those attributes and you got a talk up and running by asking the woman: "Could I ask you
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    for help? Could you tell me why/what/how/...". Ask her any question you like as long as
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    the question is non-answerable by a simple "Yes" or "No".

    Bel
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ieve it or not, but maybe you have failed in your last dating attempt because you maneuvered
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    yourself into dead-end answers. If you ask a girl "Have you been long here?" then prac
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    tically anything she can answer is a dead end. She could answer "No, not long" or
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    "A couple of minutes" but both answers do not lead into a nice conversational flow.
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

    Many men (since men are practical-minded) want a "clear and simple" answer. For dating
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    purposes that kind of "questioning strategy" is absolutely wrong.
    Train by simply
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    re-phrasing some of your question. Wrong: "Do you like this place?", right: "What
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    do you think about this place?". You get the idea. In other words: Let her TALK. (
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    This is just a simple example and I am not telling you to ask women that question).

    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    Or ask her something like: "What do you think is the most common flaw men have?" or
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    >"I am writing for dating-forum.com. Could you help me by telling me what feature your ideal
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    man should have?". Let her talk for hours.

    Typical "open questions" star
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    t with


    • Why....?

    • How....?

    • What....?

    • Where/When.....?
    <
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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