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Science is more than a period or a class that you have once a day in school. Science is all around us. Science is in everything that we do everything

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

that we use, even everything that we eat! Science can easily be referred to as key element of magic and illusion. Parents know that a great way to p

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

eak your child’s interest in science is to take the boredom out of the subject and add some of the fun and wonder back in.

Making the everyday extr

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

aordinary Sometimes making the ordinary into the extraordinary is easier said than done. Many parents would jump at the opportunity to make scien

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ce exciting for their kids but they do not know where to start. Other parents look for outside resources to help them in designing science experiments

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

that they think the kids would enjoy. There are so many different resources and ideas available, below you will find just a few ideas of how you too c

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

an peak your child’s scientific interest.

• Volcano Explosion -- An exploding volcano is one of the most classic science tricks in the book. There ar

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e multiple ways to get the flowing lava effect. A recent discovery involving household items that when combined create a bubbling effect is the combin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ation of the Mentos brand breath mind and Diet Coke. When the Mentos is dropped into the bottle of Diet Coke a chemical reaction makes the soda come s

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

pewing out of the bottle. If you do not have Mentos and Diet Coke, you can try the more traditional combination of baking soda and vinegar. You will

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

et the same bubbles but without the height.

• Float or Sink -- Anyone can do this one. All you do is collect some items from around you house and hav

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e your kids record whether they think that the object will sink or float when it is put in a tub of water. You kids may be surprised to find out that

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

some of the objects that they thought would float sank and visa versa.

• Citric Acid -- Citric Acid can be used to make a number of fun things that ge

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nerally safe to handle. You can easily find recipes to make fizzy tablets that can be used in a bath or to observe in a tube.

• Solar System -- Kids

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

generally have a great curiosity for space. Consider making a mobile of the solar system or buying glow in the dark stars to place on the ceiling. Us

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

plastic or rubber balls to show how planets orbit. Use your imagination.

Make science apply to them

Science is everywhere. Take the ever opp

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ortunity possible to teach this principle. For example; a child with a cold can be turned into a chance to learn science. We can point out that there

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

is no known cure for a cold, but that we can prevent the cold by spreading and how to control contagious illnesses.

Science has no limit

The g

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

reat thing about science is that there are so many ways to experience it with your kids. Go for a nature walk, stare at the clouds, play in the rain, l

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ook for bugs, talk about how your body works, etc. As long as you are appealing to as many senses as possibly you can succeed at any science experiment

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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