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Cheek augmentation allows the surgeon to enhance the features of the face by placing implants in the cheek area. Some patients choose cheek augmentation to fill in drawn, sunken or aged schee

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ks. Others have the procedure for a purely cosmetic reason – to get the popular high cheekbone look.

Types of Cheek Augmentation Procedures

Depending on the desired look, the surgeon can pl

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ace implants laterally (on the sides of your face), frontally, or both. While having both types of implants placed can have its benefits, this type of procedure will also slightly lengthen yo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ur recovery time.

Cheek Augmentation Materials

There are five common types of materials used in cheek augmentation procedures: hydroxyapatite, silastic, Gore-Tex, polyethylene, and cadaver

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

bone. Hydroxyapatite resembles coral’s porous nature and is chemically similar to hard tissue and bone. Silastic is a type of silicone which is flexible while being stable. Polyethylene i a c

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

oral-like plastic material. Gore-Tex is a popular choice among many surgeons since the body will not reject it. Cadaver bone is sterilized bone from a donor; this is often the least popular o

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ption since it can result in painful bone grafts.

All of these materials have their pros and cons. You should give your surgeon a detailed record of your history and your desires so that he

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

an best determine which material to employ.

How It Works

After having your consultation, the surgeon will decide your plan of action. Cheek augmentation is an outpatient procedure that last

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s between 45 minutes and an hour. Along with the surgeon, you will decide whether general or local anesthetic is used. If you have any allergies or have had serious reactions to anesthesia in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the past, be sure to let him know immediately.

At this time, the surgeon will also determine what incisions will be used. While this might change during the procedure, his decision now shou

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ld tell you what possible complications you could face.

Incisions can be made in one of three spots: the conjunctiva (or inner surface of the eye), inside the mouth or in the crease lines ou

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tside the eye. Many surgeons prefer to cut inside the mouth so that no scars are visible.

Recovery

Full recovery from a cheek enhancement procedure ranges from one to two months. However, y

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ou should be able to return to your normal routine within a week. A small, usually unnoticeable amount of swelling may remain for up to five months.

Before your procedure, your surgeon will

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

give you a prescription for antibiotics that you should begin taking diligently. Make sure you take the full round of medicine. The doctor will also prescribe some type of pain medication. Du

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ing the first few days of your recovery, monitor your temperature closely. If you have a fever that may be the sign of an infection; call your doctor immediately.

After surgery, you must car

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

efully care for your incisions and sutures. They should not become moist, and you should avoid the use of all lotions and creams until the site is fully healed. If your surgeon made incisions

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

in your mouth, you will need to stay on a liquid diet until your surgeon releases you, and you must rinse your mouth with an antiseptic mouthwash, such as Listerine, several times each day.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Bruising and swelling after the procedure may result in a temporary numbness until the swelling dissipates; if the numbness continues, contact your doctor. Cold compresses will help keep the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

swelling down. You should also be sure to stay in an elevated position for the first week. Remember to have plenty of pillows around so that you can sit up to read a book or watch television

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

.

Although you can’t be involved in strenuous exercise for several weeks, you should still be up and moving during your recovery. Staying too still while recovering can result in blood clots

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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