E-Articles - Health and Fitness

So it is time for school again and one of the things that many teachers will face this year just like in the years past will be the battle of the head lice.

It simply does not

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

matter if you are rich or poor, if your hair is short or long, or if your hair is dirty or clean, head lice really aren’t all that picky, they simply love a hair shaft. So if yo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

have one then you are at risk for getting head lice.

There are three kinds of lice that can infect humans.

Each of the varieties of lice have different characteristics and ex

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

perts vary over whether they are all even the same species. Head lice, body lice, and pubic lice all create problems of their own. The head louse is common while the body louse

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s rare.

The body louse can be found on people living in unsanitary, crowded conditions and where people wear the same clothes for days. Pubic lice, also known as crabs, invade

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the pubic area and are transferred from person to person by intimate contact.

The most common of all the lice in the United States, these little buggers are a significant probl

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

m for school age children. While they are known to be spread by physical contact, lice can be found all types of conditions, including both sanitary and unsanitary conditions. O

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

f all the folks in the US who endure head lice, 75 percent of those suffering with lice children under the age of 12.

While the numbers of those suffering with head lice are hi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

her for girls, it certainly does not mean that boys are exempt from lice infestations. With school children, it is easy for the infestations to be passed on from the child to an

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

other member of the family.

These little critters love the hair shaft and they aren’t that particular about where they live. If one person is infested with lice, it is easy for

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the rest of the family to be infested. Because of the shape of the hair shaft, those of the Caucasian decent have more infestations of head lice.

Head lice are reddish-brown in

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

color and they are wingless. Because the poor little things are wingless, they are incapable of leaping from one person to another. The adult female head lice is only 1/8 inch

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ong and the adult male is 1/10 long.

Female lice are busy little mamas, laying anywhere from 50 to 150 eggs. Less than half the size of the head of a pin, these eggs called nit

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s, are shiny white and they securely glue themselves to the hair shaft as close to the scalp as they can snuggle. The eggs hatch in approximately five to ten days and they then

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ecome known as nymphs.

In three weeks time the little nymphs shed their skin three times and then they are pronounced to be an adult head lice.

With a mild infestation, the li

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ce are found around the ears and along the hairline at the back of the head. However, with a more serious infestation of head lice, the entire scalp may be covered and as disgus

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ing as it sounds you may even see nits in the eyelashes! Totally gross!

The itching related to head lice can be more intense at night which can even begin to interfere with sle

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ep. Scratching while asleep and then scratching another area of the body can even lead to a secondary infection, making things even worse. With extreme cases of head lice, you m

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ght even see other symptoms such as fatigue, rash, chills and even leg cramps.

Head lice must be treated to assure a complete eradication of the problem. If the over the counte

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

r head lice treatment doesn’t take care of the issue then contact your physician for the best course of action for you and any family members suffering from a head lice invasion

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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