E-Articles - Health and Fitness

A stroke or the so called brain attack causes a serious injury to the brain. It is connected with blockage of the blood sup

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ply to the brain or with bleeding inside the brain. In both cases brain cells stop receiving the oxygen and the other subst

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nces needed to function normally and start dying.

If you are at a risk of having a stroke you should be prepared to react

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

specially if you live alone. Many people in this situation wonder how to recognize stroke symptoms, if they will be able to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

notice the warning signs early enough and to call for help in time.

First of all make sure you know stroke signs. Numbness

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

or weakness of the face, arm or leg, especially on one side of the body, confusion or trouble speaking or understanding, tr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

uble seeing in one or both eyes, trouble walking, dizziness, loss of balance or coordination, severe headache, with no know

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

cause – there are some of the stroke symptoms. In most of the occasions they occur suddenly and just in rare occasions dev

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lop in time. While it is possible another medical condition to be causing any of the above, you better seek help immediatel

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

. Quick reaction and urgent medical help are vital when it comes to stroke and the related damages.

Some people worry if s

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

roke happen during their sleep. Of course it is possible, however it is not necessary that you will woke up if some stroke

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

strikes. You may experience some of the symptoms when you woke up in the morning, in which case call your doctor right away

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

If you woke up in the middle of the nigh bothered by some of the above warning signs also seek help right away. A common m

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

stake that many people make and that unfortunately costs their life is that they go on sleeping hoping that the symptoms wi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

l be gone in the morning.

Finally do not underestimate mild strokes. A mild stroke or transient ischemic attack (TIA) is c

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

used by a temporal interruption of the blood supply to the brain. It results in a brief decrease in brain function and the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ymptoms may be subtle or fleeting. A TIA may last an hour or even less. Do not feel relaxed that the problem has passed. A

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

IA is a serious stroke warning sign and it usually comes to alert you that a serious stroke may happen in minutes, hours or

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

a day. If you feel even slightest stroke symptoms seek help. Even if the symptoms are gone by the time your doctor comes, h

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

will be able to evaluate your condition and even hospitalize you for monitoring and prevention of a possible future stroke

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - What Should You Do if You Think You are Having a Stroke?

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