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Headaches, insomnia, anxiety and constipation have the same root cause which is a vata imbalance according to ayu

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rveda. Until recently modern Western medicine believed that health was simply the absence of disease. Illness was

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

caused purely by something outside the body, the way a hammer hitting your toe causes pain—viruses caused colds,

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

llergens caused allergies, stress caused anxiety, carcinogens caused cancer, and so on. The solution was to find

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he right pill and the disease would be cured.

But today we know that the seeds of illness are sown way before ob

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ious symptoms appear. The absence of a readily diagnosable disease is no longer the definition of health—people w

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ant to feel good, not just "not bad." The hammer-hitting-the-toe model of disease doesn't explain the wide variat

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

on in people's abilities to resist illness or recover from illness. When you encounter a cold virus, you have onl

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

one chance in eight of getting a cold. Seven out of eight times your mind-body is able to defend itself. Clearly

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the virus is only one small factor—the state of your general health is paramount.

By focusing on physical cause

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nd effect Western medicine has looked at individual organs in isolation, as separate from one another and from th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e mind and spirit. By way of contrast ancient civilizations were intimately in touch with their nonphysical selve

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

and had rich inner lives. They knew what modern science is just now starting to realize: The mind and body are s

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

connected as to be indistinguishable from each other.In many ways modern science is only beginning to catch up w

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

th Ayurveda. In many ways modern science is only beginning to catch up with Ayurveda. For example research is dis

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

overing that certain people are constitutionally prediposed to certain illnesses, and proving that lifestyle prac

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tices and gentle herbal medicines can make a huge difference in our ability to resist disease, recover from illne

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s, and extend our lives. That's exactly what the ancient science of Ayurveda has been saying for thousands of yea

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s. Headaches, insomnia, anxiety and constipation have the same root cause which is a vata imbalance and this is a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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