E-Articles - Health and Fitness

Pain is experienced by everyone and is usually manifested with trauma, to a certain part o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

f the body. It is basically the transmission of the nerves, communicating and passing nerv

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

messages through the neurons.

Back pain is quite common and people suffering from this t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

pe of pain rely on both, age-old therapies as well as the modern techniques, for their tre

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

atment. The age- old therapies, such as massaging and acupuncture have all been tried, to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

lleviate the pain. All these treatments claim to be effectual in reducing and at times o

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

literating back pain. However, there is no parameter to assess the accuracy of their claim

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

. Patients have had different individual experiences that cannot be generalized.

Physioth

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rapy and exercise also play an important role in controlling the pain. It has also been pr

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ved statistically that back pain can be treated with alternative medicine. Back pain is a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ommon occurrence in large sections of the population and the oral medication available is

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

usually sufficient to subdue it. Surgery is recommended only in a few cases of severe back

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

pain. Most patients prefer to seek other the recourse of alternative medicine. The alterna

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ive remedies are effective in reducing the pain and tense muscles, without the help of med

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ication.

Back pain can be an acute or chronic disabling condition. At times, an acute low

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r back pain may be caused by a traumatic event, such as a car accident or a fall. In such

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ases, the soft tissues, muscles, ligaments and tendons are damaged, resulting in unbearabl

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e pain. In the case of a serious accident, vertebral fractures in the lumbar spine may als

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

occur, which is manifested in the form of excruciating pain. It is advisable for the pati

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nt to consult a doctor and have an x-ray taken, before indulging in any kind of medication

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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