E-Articles - Health and Fitness

"I felt 10 years younger right away!" says Margaret, age 59, after she tried hyaluronic acid facial fillers to smooth out the lines from her nose to the corners of her mouth

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

and plump up her lips. "People really noticed!" Margaret maintains her new look by having hyaluronic acid injections every six months. "Each time I get a treatment, the effec

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ts seem to last longer," she says.

Now researchers have found a scientific basis for the results that Margaret and many other woman and men have noticed. A new study shows t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hat Restylane, a popular injectable anti-wrinkle treatment, appears to stimulate facial skin cells to make their own collagen, a basic skin protein. This research was reporte

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in the Feb. 20, 2007 Archives of Dermatology, published by the American Medical Association.

The clinical study showed that Resytlane's initial anti-wrinkle effect

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

is caused merely by the presence of the filler in the skin. But three or four weeks after treatment, the skin actually begins forming its own new collagen.

What is

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hyaluronic acid?

Hyaluronic acid is a naturally occurring sugar in the skin that holds collagen and elastin together. This essentially provides a framework for the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

skin.

Injectable fillers such as Restylane and Juv?derm plump the facial skin, adding volume to minimize lines and wrinkles. These hyaluronic acid fillers work by pulling w

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ter into the skin. Patients notice the results immediately.

Since the clinical study on Restylane, the Food and Drug Administration has approved Juv?derm, an injectable hyal

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

uronic acid filler introduced by Allergan in January 2007.

Hyaluronic acid fillers surpass collagen injections

Hyaluronic acid fillers are extremely popul

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ar among busy women and men seeking less-invasive procedures to address the signs of aging. According to the American Society for Aesthetic Plastic Surgery (ASAPS), Americans

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

received 1,593,554 injectable hyaluronic acid treatments in 2006 -- making this non-surgical facial enhancement second in popularity only to Botox. Hyaluronic acid injection

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

are normally given every six to 12 months.

Both Restylane and Juv?derm are available in several formulations to treat fine, medium and deep lines and wrinkles. Hyaluronic a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

cid fillers are most commonly used to plump up the nasolabial folds, which extend from the nose to the corners of the mouth, as well as lines in the glabella, or the

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

area between the eyebrows. These facial fillers can also add fullness to thin lips, smooth out acne scars or pits, and diminish vertical lip lines known as smoker's lines.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Allergic reactions are rare

Another reason for the rise in hyaluronic acid-based fillers: fewer allergic reactions. Because earlier facial fillers such as

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ollagen were derived from cows, patients had to undergo a pre-treatment skin test for allergies, then make a separate appointment for their first treatment.

But unlike colla

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

gen, hyaluronic acid is a natural component of the skin, so no pre-testing is required and allergic reactions are rare. Patients can normally be treated on their very first d

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

octor visit. And hyaluronic acid poses no risk of transmitting animal diseases by injection.

With the popularity and precision of hyaluronic acid facial fillers, the use of

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

collagen injections has plummeted. The ASAPS reports that 160,252 collagen treatments were administered in 2006 -- a reduction of 52% among women and 83% among men since 1997

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.e-article.org.ua/article/232343/e-article-Baby-Boomers-Rely-on-Hyaluronic-Facial-Fillers-to-Look-Younger-in-Minutes.html">Baby Boomers Rely on Hyaluronic Facial Fillers to Look Younger in Minutes</a>

BB link (for phorums):
[url=http://www.e-article.org.ua/article/232343/e-article-Baby-Boomers-Rely-on-Hyaluronic-Facial-Fillers-to-Look-Younger-in-Minutes.html]Baby Boomers Rely on Hyaluronic Facial Fillers to Look Younger in Minutes[/url]

Current or potential Website owners investigating affiliate programs will no doubt discover the huge and baffling variety of sites on offer.

Internet paid surveys may be your answer to recoup your recent tax payments. Fortunately, the tax season is over! So it is time to think about how we can all recover the negative equity and start building our savings again. Let us see if internet paid surveys can really help one to quickly get into the black and earn some cash real quickly.

The allergy - hypersensitivity of an organism of the person to some substances - represents the hyper reaction developing in reply to influence of alien substances - allergens. The reason of occurrence of allergic reaction of an organism is infringement of immunity.

Tags

Links

E-Articles - Baby Boomers Rely on Hyaluronic Facial Fillers to Look Younger in Minutes

Related Articles: