E-Articles - Health and Fitness

Soap is something I am very particular about, because of the properties it contributes to bodily hygiene all round.

So in my opinion soap needs to be full of nat

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ural ingredients such as fruit, lye and herbs. Soaps are something everybody I know uses at one time or another. It is great with natural ingredients, refreshi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

g is the word I'm looking for. Would you like me to tell you how to make your own soap? It is as easy as this, You take some caustic soda and Combine it with some

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

fat using water as your main catalyst.

Performing a method that is very important in soap making, The name we use for this process is called saponification the t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

chnical name for the working of fat and lye. People may think that you need lots of exotic ingredients that are hard to find to make soap. On the other hand thei

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

r are lots of ingredients to choose from out there,

and they can be found near by in places like your local fruit and veg store. Fresh herbs are a rich source of

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

natural soap making, the use of scented oils are also a key factor in the process.

For me I prefer to use ingredients that enhance my soap like lavender a cool b

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t robust scent.

Sometimes people have been known to use distilled water or rain water but if you cannot get them then just go to the tap it's easier, although I

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ust say that distilled water is my personal favorite.

Some of you may be thinking what is lye? It's a chemical base, called sodium hydroxide it's very strong so

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

be very careful in using lye.

The first step to making your own soap is to dissolve the lye, but don't add the water to the lye. It is very important that you po

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r the lye into the water, and in my opinion it is always best if half the water is ice cool. Then you stir slowly watching closely for the reaction that the water

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

gives with this mixing process. You don't want the mix to start to react in a way that it looks as if it is boiling. If you notice this happening you must stop st

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rring immediately and give the mix time to cool, room temperature is good.

Oil is the next ingredient I would like to introduce, you may use any type of oil. Let

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

me give you a few examples, you may use oils that are extracted from plants like roses and geranium. other oils or fats that are popular are animal fats and vege

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

able oils. My personal favorites are coconut and olive oils, coconut gives your soap that rich texture while olive oil will give that clear sort clean look.

As f

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r the animal fat it's not recommended but if you have to use it then make sure it is clean and salt free.

It needs to be solid particle free, you will find that

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

allow or lard will be the best choices in animal fats, because they make your soap more wholesome but yet gives a more dense feel.

By this point your batch will

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

have started to thicken now you may add perfumes coloring and oils. The next step is to pour the soap trace into your mold then leave to harden. You will have to

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

give a curing time of 1-2 days before its ready. But wait a little longer before you can truly enjoy your fresh homemade soap.

The properties of handmade soap ar

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the oils, herbs that relax you after a hard days work, as they help you connect with yourself, if you know what I mean. So get soap making.

By Andrew Dekannwarr

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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