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Depression has become recognized as a potentially dangerous disease by doctors in the past several years. Unfortunately, it hasn't always been th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is way. People used to be labeled as hypocondriacs, whiners, lazy, ect. You get the picture.

However, there are now many famous people that have

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

come forward and shared their disability with others. People like former NFL and Hall of Fame Quarterback, Terry Bradshaw, Actress Linda Hamilton

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

of " The Terminator" and "Beauty and the Beast" fame, came forward a few years back and stated that she too suffered from depression.

The avera

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e person could have depressive symptoms and not be aware that they could have a very real problem. Many people are in denial that they could have

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

anything like that happen to them. Some of us tend to have a "super hero" mentallity, where admitting that we could have a problem such as depres

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

sion might make us (God forbid!) human.

Here are three signs that you could be suffering from symptoms of depression.

#1. You feel crummy, don'

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

know why, and it lasts at least two weeks.

I'm talking about lack of energy, sadness, possible crying episodes, ect. You've either never, felt

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

his way or at least not for this long. You could be moody, have a lack of enthusiasm, loss of interest in things that you normally like to do, ec

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

. Maybe your wife, kids, co-workers, relatives or friends notice that something is wrong with you. You could also have a loss of sex drive.

#2.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ou have thoughts of hurting yourself or others.

This is pretty self explanatory. If you feel that you're a "normal" guy or gal and you are all o

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

f the sudden having feelings of harming yourself or others, then it's time to seek professional help.

This is potentially a symptom of what's kn

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

w as Bipolar Disorder or more commonly known as Manic Depression. Many manic depressives will resort to self mutilation as a way of crying for he

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

p. Razor cuts on the arms are quite common. I know that this doesn't paint a pretty picture. As I stated before, depression is a potentially seri

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

us disease.

If you or anyone you know suffers from symptoms like this, please seek medical help right away.

#3. You want to isolate yourself fr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

m others.

Everyone needs privacy at times, but I'm talking about when you just don't want to be around others for any length of time. Perhaps yo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

u're having symptoms of anxiety, such as heart racing, chest pains, sweaty palms, rapid breathing, ect.

Anxiety and depression can go hand in ha

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d. There are many individuals taking medication for both symptoms at the same time.

Summary

Depression is nothing that you have to be ashamed o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

. It's quite common and there's a very good chance that your doctor can prescribe some form of medication that can help to curb your depression a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d/or anxiety symptoms.

So if you've been feeling down for more that two weeks, get yourself in to see your doctor and get yourself back on track

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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