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Agoraphobia

If you hear about someone being agoraphobic, you get the immediate mental image of a recluse who hides from people. You would also figure that a person with agoraphobia would avoid social situations. But if you did, you would be wrong.

You have heard of mental disorders. Yo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

u might think only mentally unbalanced people become afflicted with these conditions. However this is simply not the case. Mental disorders include panic attacks, anxiety disorders and social anxieties as well. These attacks can range from mild discomfort to debilitating agoraphobia and this is

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

a condition that can strike anyone.

Panic and Anxiety Attacks

Your life is going along the normal path that you’ve set out when suddenly without any warning terror has you in its grip. You feel weak and helpless. Your heart’s pounding and you have trouble breathing. You may even wonder

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

if you’re having a heart attack or if you’re about to die. When you finally go to see a doctor, you might even be told there’s nothing physically wrong with you. So when you next suffer from an attack you wonder what’s wrong with you. You find that certain situations will bring on these frigh

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ening attacks and this will be your first clue that you’re experiencing a panic attack. Panic attacks are not physical conditions, and that is why your doctor might have had trouble diagnosing your complaint.

Panic and Anxiety Attacks what’s the difference?

Anxiety attacks are like a f

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

eling of dread. You don’t want to do something or go somewhere. You feel uneasy and my have light physical symptoms like an irritable stomach but for the most part anxiety attacks have little physical symptoms. Panic attacks on the other hand manifest physical symptoms such as painful feelings

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n the chest, heart racing, unable to catch ones breath or a feeling of drowning or choking. Often people use the terms anxiety and panic attacks interchangeably. This is incorrect, but since there is a gray area where they overlap people have become accustomed to using them interchangeably.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

>Misconceptions So, what is agoraphobia you might ask then? This is a condition where an individual doesn’t wish to go places or face situations where they could become exposed to panic attacks. The very word agoraphobia itself lets us know the nature of this debilitating condition. ‘Agora

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

comes from the Greek language and it means places where people meet, or a marketplace. ‘Phobia’ is a fear of something. Thus many believe that agoraphobia is the fear of crowded places when in fact it’s a misconception that agoraphobia is a fear of "crowded spaces.

Agoraphobia Is Related T

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

The Pain of Panic Attacks

Agoraphobia is a condition that develops gradually. In general it occurs after a panic attack. After the first attack you may subconsciously be preparing for another attack and fearing the symptoms that will leave you feeling helpless. This cycle of panic attack

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nd impending panic attack can cause you to change your entire lifestyle just to avoid those feelings of terror. As panic attacks can occur anywhere at anytime, we generally associate the first place that we feel helpless as perhaps the reason for our terror.

An agoraphobia sufferer will go out

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

of their way to avoid those places and situations where a panic attack may occur. They may even end up being housebound as they avoid being in crowded places. This unhealthy lifestyle can in itself trigger agoraphobic attacks to occur in everyday normal situations. The increased heart rate may

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

lso cause a panic attack because you may think that you’re having a heart attack.

As you can see this is a vicious and extremely debilitating mental condition. For sufferers of panic attacks they should seek the medical aid of doctors who specialize in these mental disorders and receive treatm

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nt before their panic attacks spiral into agoraphobia where they may end up being restricted in their lifestyle due to their ever-increasing fear of being helpless in the face of a panic attack.

Occurrence and Diagnosis

Most people develop agoraphobia after the onset of Panic Disorder.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Panic disorder is simply recurring Panic Attacks. About 2 percent of the population will at one time or another face Agoraphobia or Panic Attacks. Usually women are twice as likely to be overcome with Panic Attacks and Agoraphobia. It is important for you to understand that Agoraphobia is the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

adverse reaction to repeated Panic Attacks and not a physical condition.

Treatments

The most common treatment for Panic Attacks and Agoraphobia are the use of anti-anxiety or antidepressant medications. Also a gradual process of exposure therapy will help one overcome the cycle of Pani

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Attacks and Agoraphobia. A qualified physician or therapist must oversee this process. Some other things to try are Meditation, Yoga or some other sort of exercise. This will allow you to begin to control the Panic Attacks. It is also important for you to change the wording of your inner voic

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

. You must eliminate all negative thoughts and replace them with positive ones.

A great resource for you to eliminate Panic Attacks and Agoraphobia is the ebook A Step By Step Guide To Curing Your Anxiety and Panic Attacks-"Cure Anxiety In 8 Weeks" This step-by-step guide is available from h

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tp://overcomeanxietyandpanicattacks.com/cure_anxiety_in_8_weeks.htm

It is also has an audio-book version that will make it much easier for you to take in all the information it gives you. Delivered as a downloadable MP3 you can listen to it on your computer, mp3 player or you can make an audio

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

CD that you can listen to in your car or anywhere you have a CD Player.

Steve Knorr is the Author of the above article, all rights reserved. You may publish this article on your website or ezine as long as you leave all links in the article and the resource box at the end. (C) 2006 Steve Knorr

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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