E-Articles - Health and Fitness

What Are the Symptoms? You may be ‘clinically’ depressed if you have most of the following symptoms:

depressed mood most of the day, nearly every day, that may be noticed by othe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rs.

Loss of interest or pleasure in all, or almost all, activities most of the day, nearly every day

significant weight loss when not dieting or weight gain or decrease o

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r increase in appetite nearly every day.

insomnia or hypersomnia nearly every day

psychomotor agitation or retardation nearly every day

loss of energy nearly ev

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ery day

feelings of worthlessness or excessive or inappropriate guilt nearly every day

diminished ability to think or concentrate, or indecisiveness, nearly every day

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

epression Test: Below is a common depression test developed by the psychiatrist Ivan K. Goldberg. The test result is NOT a final diagnosis! The scale cannot replace professional help. If yo

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

u suspect that you might suffer from depression, you should contact your doctor, no matter what test result you get.

I have posted this test so you can see whether you have symptoms

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

of depression or not and its severity. You can also use the scale to see if you are making progress in your recovery from depression. If you want to, you could print out the test and show i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t to your doctor. This might help him or her to assess your condition better.

The questions below refer to how you have felt and behaved DURING THE PAST WEEK. For each question, ind

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

icate the extent to which it is true, by using the following scale:

0 = Not at all 1 = Just a little 2 = Somewhat

3 = Moderately 4 = Quite a lot 5 = Very much

The

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

uestions:

I do things slowly
My future seems hopeless
It is hard for me to concentrate on reading
The pleasure and joy has gone out of my life

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

I have difficulty making decisions

I have lost interest in aspects of life that used to be important to me

I feel sad, blue, and unhappy

I am agitated and k

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eep moving around

I feel fatigued

It takes great effort for me to do simple things

I feel that I am a guilty person who deserves to be punished

I feel

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

like a failure

I feel lifeless - - - more dead than alive

My sleep has been disturbed---too little, too much, or broken sleep

I spend time thinking about HOW I

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

might kill myself

I feel trapped or caught

I feel depressed even when good things happen to me

Without trying to diet, I have lost, or gained, weight

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

>

Now add up your total score. According to Goldberg if you scored: 0-9 Depression is unlikely
10-17 Possibly minor depression
18-21 Possibly on the verge of depression

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r> 21-35 Possibly minor to moderate depression
36-53 Possibly moderate to severe depression
54+ Possibly severe depression

Please note that this test result can

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

not give a you guaranteed assessment of your mental health. You should always consult a doctor if you feel depressed or if you feel that worries and anxiety have taken over and affected the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

activities of your daily life. Seeing your doctor and getting the right treatment quickly will dramatically improve your life, and the life of those who care about you.

I sincerely hope thi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s helps. Don’t forget you can freely post your stories and feeling of living with depression and low mood on SpeakOut’s Forums (http://www.speakout.biz/forum).

I wish you the best of health

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.e-article.org.ua/article/239245/e-article-Are-You-Depressed.html">Are You Depressed</a>

BB link (for phorums):
[url=http://www.e-article.org.ua/article/239245/e-article-Are-You-Depressed.html]Are You Depressed[/url]

Increase Website Traffic and Activity with Articles Containing One Way Links to Your Website

Relevant, high quality, and original article writing is a proven way to increase website traffic and activity. One of the reasons is, article writing provides one way links to your website. You write a compelling article and finish the article with up to 3 one way links back to your website.

Online Dating Tips for Men

Women online receive hundreds of emails. Men on the other hand receive a handful. Here are five basic tips to help meet women online. Tips such as honesty, template letters, protecting your identity online and scams.

Destination Wedding Etiquette

The wedding is all set for romantic and enchanting on the isolated island, great hideaway, mountain alpines, and panoramic castles. Here is list of etiquette for proper manner and behavior on destination wedding.

Bookmark it:

Tags

Links

E-Articles - Are You Depressed

Related Articles: