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If you’re currently someone who is treating depression, you should be asking the question ‘is depression real or is it just a label?’ I often ask myself this question or at

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

least I have in the past. After years of soul searching, going through stages of my life where I have delved into the darkest portions of my being through to running a mill

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

on miles an hour from the sometimes painful truth, I’ve discovered that labeling myself as 'depressed' doesn't really help. In fact I've come to the conclusion that buying

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nto the label of 'depression' often gives us an excuse to avoid looking at the truth, which is there within all of us.

So what is depression? Its different for everyone, b

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t for me I could probably sum it up as a combination of loneliness, intense sadness, suppressed anger, self hatred, and a severe lack of acceptance for my self and the prese

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

t situation. From what I have observed in myself and those close to me, it is a result of a deep seated desire to change who I am, and find a recipe for avoiding pain, fore

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

er. However, an important thing to realize when treating depression is that there is no recipe for happiness, there is no recipe to avoid pain.

The best avenue to treating

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

depression is to accept ourselves as we are. How do we do this? That involves a fundamental shift in the way we think. Why not start by instead of seeking happiness (as

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

distraction from what is really going on) and avoiding pain, why not seek out our pain and give our happiness away (instead of suffocating it). Even better learn to just b

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

with ‘ourselves’ no matter what the discomfort. If you are truly seeking a natural alternative to treating depression, meditation is essential.

The best way to overcome d

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

pression is not to try to overcome depression. If we use the usual mindset, ‘trying to change ourselves’ it means that we end up subconsciously reaffirming to ourselves tha

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

there is something wrong with us. In treating depression it is essential that we overcome this cycle, but it’s not easy. Meditation gives us the opportunity to do this, or

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

at least practice this each day.

Meditation isn't about visualizing, it isn't about imagining a better life, and it’s not even about thinking positive thoughts. It’s about

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

becoming present with your own version of reality. It’s about learning about who you are, and in the process, accept yourself. Basically meditation is a way of life, its s

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

omething that affects us subtly and gradually over time. Meditation is a long-term solution to treating depression; therefore you may have to accept that it is not somethin

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

that will magically change overnight.

I remember when I first began meditation as a form of treating depression. It was at a time when I was really struggling with depress

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

on and life. I had sought out just about every alternative to treating depression that I could think of, and I didn't want to go on medication. A lot of different things ca

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e up when I was trying to meditate. Things like, I thought I wasn't doing it good enough, there was something wrong with me, I’ll never get there, its a waste of time. To b

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

honest it is pretty amazing that I stuck with it. All of these thoughts are natural. I remember having a good friend whom would remind me every time I would feel to just o

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

serve myself. That is the essence of meditation

For more information on treating depression and meditation techniques, click on the link to my website, The Depression Trap

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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