E-Articles - Health and Fitness

Anxiety and depression are the two traits of human mind, which crop up as a result of our action to different situations. Having anxiety o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

r depression is common to all and they have their own role to play in our lives; normally they instigate a human being to take corrective

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

actions to straighten the situation. For e.g. Lets say you have a problem because of which you get depressed or worried, isn’t it a normal

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

situation we all undergo? And getting worried about it only means that you are concerned about it. Now because you are worried you will t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ake necessary actions to solve the problem. Tell me; had there been no worry would you have made an effort to solve it?

But the big quest

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ion is if having anxiety or depression is normal then why is it called a disorder? Anxiety turns into a disorder when you just worry and d

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

o nothing to solve the problem or when you are unable to gather the required courage or enthusiasm to take an appropriate action. Anxiety

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

and worry becomes overwhelming and effects the normal functioning of life. In this situation you need to find out the reason behind your m

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ental condition and seek help from family or friends or even professional counselor.

A few tips for self-analysis and self-help are given

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

below for you, if you think you are suffering excessively from worry and depression.

• Exercise and Walk! At least for 20 minutes everyd

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

y! This is the most effective way of controlling high cholesterol, lower hypertension, reduce anxiety, lighten depression, and stop panic

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

attacks dead in their track!

• Maintain a journal everyday and write down your reasons of depression, worries and fears.

• Analyze your

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

fears, are they real threats? How much is under your control? Are you taking too much pain for something which is not that big as you are

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

deeming it to be?

• Are you sleeping properly? Sleep well and take effective measures if you are not able to sleep properly.

• Talk to a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

trusted friend about your worries and fears. He will be able to help you in finding out the exact problem.

• The best way to combat anxi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ety and worry is to face the threat. You have already evaluated the seriousness of the issue. Now make an action plan and work on it.

The

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

realization that you are not behaving normally in normal or tough situation is the first step towards your wellbeing. Now, its time to se

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ek help from your family or friends, they may help you understand the severity of your mental condition and find you a good psychological

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

counselor for your treatment if required. Speak out your mind. This is the only way to get help from people around you, who care about you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

. Remember, this situation of turbulence is not permanent. A happy and peaceful life is waiting for you; you just need to walk up to there

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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