E-Articles - Health and Fitness

You've just been diagnosed with diabetes; not a life sentence! Sure, you have some new guidelines that need to be followed, but they are

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

doable. In fact, you'll probably be pleasantly surprised how much fun you can have on your journey to better health. You can have fun a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

you manage your diabetes through exercise.

Exercise. It's become a four-letter word these days because it involves commitment. It

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

has also been described as boring, time-consuming, and embarrassing.

Despite the bad rap exercise has gotten over the years, it is f

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

un and greatly benefits your health. Did you know exercise actually prevents the progression of diabetes?

How Do I Prepare to Exerc

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

se Properly?
Well, here's the part where I'm going to sound like your mother! "You should check with your doctor before you start e

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ercising!" It's true. This checklist includes seven quick and easy steps before you get out and exercise:

1. Talk to your doct

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

or about the right exercise for you.
2. Check your blood sugar level before and after exercising.
3. Check your feet for blis

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ers or sores before and after exercising.
4. Wear the proper shoes and socks.
5. Drink plenty of fluid before, during and aft

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r exercising.
6. Warm up before exercising and cool down afterward.
7. Have a snack handy in case your blood sugar level drop

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

too low.

There is only one rule when you manage your diabetes through exercise – and that is to make sure you're safe: go slowly.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Gradually increasing the intensity and length of your workout as you get fit is a sure way of ensuring your safety and health.

What

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

xercises Are Safe For Me To Do?
Okay, you have your comfy workout clothes on, you have your water bottle, you have your favorite tun

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s playing, you've stretched out, you're ready to go… but, "Where am I going?" you might ask, or, "What exercises am I going to do?" Two

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

categories of exercises that are sure to match your own personality and abilities are:

1. For those who have problems with the nerv

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

s in your feet or legs, these anaerobic exercises are a perfect match for you: swimming, bicycling, rowing or chair exercises.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

2. For those who don't have problems with the nerves in your feet or legs, these aerobic exercises are a perfect match for you: walking,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

jogging, aerobic dance or bicycling.

What Do I Get Out of It?
You may be asking, "If I put all my time and heart into it, what

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

is exercising going to do for my diabetes?" The following benefits to management diabetes take place through exercise:

-Weight loss

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

-Lower blood sugar levels
-Lower risk of heart disease
-Overall health improvement
-Self-esteem
-Self-confidence

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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