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  • E-Articles - Diabetes Disease A Burning Problem For Our Human Society

    Diabetes is of two types they are diabetes mellitus and diabetes insipidus. Diabetes is a metabolic disorde
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    r caused by insufficient production of insulin produced by the gland called pancreas. Anti diuretic hormone
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    , insulin is responsible for the absorption of glucose into the cells to generate energy,if the production
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    of insulin is less ,energy produced will be low and so diabetic patients are found to be dull and sleepy.De
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    fects caused due to the deficiency of insulin are less synthesis of insulin from the beta cells. Let us now
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    study about the types of diabetes.

    Types of diabetes mellitus are
    1. Insulin-dependent type.
    2
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    . Non-insulin dependent.
    Reasons and causes for diabetes - Diabetes is mainly caused due to various re
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    sons such as viral infection that damages the pancreas causing the deficiency of insulin, obesity (major ca
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    use) leading to development of non-insulin dependent diabetes.

    Symptoms:
    Polyurea - excretion of inte
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    rested quantity of urine.
    Polydipsia - excessive thirst leading to increased consumption of water.
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    Polyphagia - excessive appetite leads to increase in take of food. In spite of over eating, diabetic pati
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ent looses weight.

    Important Diabetes Q and A
    How much weight should I lose each week?
    Restraini
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ng your weight loss to 1/2 to 1 pound a week will keep you body healthy and perfect, and enjoy your favorit
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    e food in small amount. This is the key for you to lose weight slow and steady.

    How can I cut the fat in m
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    diet?
    Here are some basic tips,Firstly see a dietitian for more advice. Avoid fried stuff's choose n
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    onfat or low-fat selections, such as no fat or 1% milk or cheese containing low fatty foods and less choles
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    trol foods.

    Why does losing weight help my diabetes?
    Lowering Insulin resistance will allows the natu
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ral insulin to lower the blood glucose level in the body. Secondly this will improve blood pressure and inc
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    rease fat present in the blood. People suffering from Diabetes will (mostly) become prey for cardiovascular
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    diseases. Reducing fat present in the blood and blood pressure reduces the risk of cardiovascular diseases


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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