E-Articles - Health and Fitness

Diabetes is a disorder of the body’s sugar-absorption and utilization abilities, and hence the o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nly possible way to bring sugar levels back to normal may be by avoiding sweets. But it is not n

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ecessary that you sacrifice your favorite dishes or sweets. If a balanced meal, specific for the

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

person is planned, the sugar levels can be controlled. If such a diet is maintained on a regula

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

r basis it can even reverse the signs of diabetes. And it does not mean that the food has to be

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

bitter or flavorless. There are many options to choose from, but the main idea is to choose the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

right food.

Do not think of this as a big task. With the help of a doctor or dietician the righ

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

meal plan can be arranged for you. And there is good news, because you will be choosing healthy

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

food. Your overall health will be improved, protecting you from obesity, cancer, heart disease

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

and hypertension. The various options that help you follow and keep up with your meal plan are

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the food guide pyramid, rating your plate, carbohydrate counting and exchanges lists. Any one of

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

these will be suitable for you.

The other ways to be sure you maintain your diet is by keeping

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

a diary and noting your daily food intake. Be consistent in your diet, and do not eat bad food

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on one day thinking you can compensate for it on another day; this will only weaken your plan.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

or those who love sweets there is no reason to worry, as there are many healthy food options tha

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t are sweet. For example, a slice of fruit could be taken along with the meal. Also, you do not

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

have to completely avoid sweets. Taking sweets in very small portions may help. You could also u

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

se sweeteners like honey, brown sugar, molasses and cane sugars. Reduced-calorie sweeteners like

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

mannitol or sorbitol can also be taken as a substitute for normal sugar.

If all these points a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

re followed on a regular basis you could start living a normal life even though you are diabetic

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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