E-Articles - Health and Fitness

Who do you blame for being sick? Think back to the last time you had a cold. Whose

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

fault was it? Your co-worker who sneezed on his hands and then touched your desk?

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

Maybe it was those filthy doorknobs in the gas station restroom? Or perhaps your k

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

id with all her germs?

And if it were those filthy doorknobs, why didn’t you get

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ick all the other times you touched them? Why was it just this time? Thousands of

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

germs are floating around every day. So why is it that on some days you “catch” a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

old or other days you don’t?

It’s called your immune system. Most days your immun

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e system can handle anything that comes its way. It easily fends off all attacks a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

d keeps you healthy and functioning at your best.

So why is it on some days that

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

you get sick? Well, the answer is pretty obvious: your immune system on these days

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

is weak. And the cause of this weakness? It could be many things, including lack o

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

f sleep, poor nutrition, and not remaining calm during stressful situations.

The

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ey, then, is to maintain your immune system by eating fruits and vegetables, getti

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ng a good night’s rest, and being physically active. All-natural supplements, like

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Trace Minerals (http://mortersupplements.com/traceminerals1.html), and Alka Green

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

(http://mortersupplements.com/alkagreen1.html) can also be beneficial. The reward

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

or taking care of your immune system is that your immune system will take care of

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

you.

So don’t blame your sniffling co-worker the next time you catch a cold, blam

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

yourself. By taking responsibility for your sickness, you allow yourself to final

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ly look at the cause of your ‘dis’-ease and thus change whatever that cause may be

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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