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In this article about antioxidant treatment of atherosclerosis disease, you will discover:

The fact

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s about antioxidants

Why are vitamin C and E a good treatment of atherosclerosis disease

How

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

much of vitamin C and E to take to help with the treatment of atherosclerosis disease

The

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

Facts About Antioxidants

Antioxidants are substances which help to guard your body from damaging o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

idation reactions caused by free radicals.

These damaging oxidation reactions have been linked to the devel

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

pment of degenerative diseases.

There are many vitamins, minerals, supplements and foods which act as antio

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

xidants, here are a few:

Alpha-Lipoic Acid
Bilberry
Cat’s Claw
Co-enz

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

me Q10

Copper

Ginkgo

Grapeseed Extracts

Green Tea

Lutein

Lyc

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

pene

Manganese

Pine Bark Extracts

Reishi

Riboflavin

Selenium

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Vitamin A (beta-carotene)

Vitamin C

Vitamin E

Zinc

The antioxidants which

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

re particular good for the treatment of atherosclerosis disease are:

Vitamin C
Vitamin E
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a
i>

Why Are Vitamin C And E A Good Treatment Of Atherosclerosis Disease?

Vitamin C is

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

powerful antioxidant within your body’s fluids. Studies have shown that by taking vitamin C supplemen

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s, you can lower your cholesterol and reduce the risk of atherosclerosis disease.

Vitamin E is a powerful a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tioxidant within your body’s fats. Studies have shown that by taking vitamin E supplements, atheroscle

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

osis disease progression, the development of coronary thrombosis and heart attacks can be reduced.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

How Much Of Vitamin C And E Do You Need To Take To Help With The Treatment Of Atherosclerosis Disease?
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
g>

To help with the treatment of atherosclerosis disease, you will need to take between 100-200 mg of vitam
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
n c per day and between 100 and 200 IU of vitamin E per day.

So, to sum up…

Studies have shown that
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
by taking the antioxidants vitamin C and E, that it can be an effective treatment of atherosclerosis disease

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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