E-Articles - Health and Fitness

We all overeat occasionally and feel awful because we have stuffed ourselves. Usually, we overeat because it is holiday time, we are at a special occasio

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

n like a birthday party or we are upset about something. However, if eating too much happens to you more than occasionally, you may have a binge eating d

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

isorder.

SYMPTOMS OF BINGE EATING DISORDER

If these symptoms occur more than occasionally, you may have binge eating disorder:

*Eating large amounts o

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

f food even if you are not hungry.

*Eating until you are either very uncomfortable or sick.

*Eating too much too quickly.

*Feel that your eating is ou

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t of control.

*Feel disgusted, guilty and/or depressed after bingeing.

If you suspect you have a binge eating disorder, you are not alone. It is the mo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

st common eating disorder in this country. The majority of people with this problem are overweight or obese. However, normal weight-range people can also

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

be affected by this disorder.

It is estimated that there are over five million Americans who suffer from binge eating disorder. People who are severely

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

obese are the most afflicted. It is also more common for women than for men.

There are a variety of factors that can cause binge eating disorder. For m

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

any of us, an episode of binge eating is brought on by excess anxiety, anger, boredom or grief. Many people who have binge eating disorder may suffer fro

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

m chronic depression or other emotional problems.

WHAT CAN YOU DO?

If you think you are a binge eater, you should avoid unhealthy dieting practices as

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

they can increase the urge to binge. Unhealthy dieting practices would be skipping meals, cutting back drastically on calories or limiting the kinds of f

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oods you eat.

These are unhealthy and dangerous ways to try to lose weight and they do not work. If you are a binge eater and are obese, you should go o

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n a healthy diet and exercise regimen to lose weight effectively and permanently.

If you find it difficult to stay on a healthy weight loss program and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

suffer from depression or other emotional problems, you may need to seek professional advice from your physician, a clinical social worker or a psychiatr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ist/psychologist who specializes in the eating disorder field. Sometimes it is necessary to ask for help.

DANGERS OF BINGE EATING DISORDER

Those with b

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

inge eating disorder are frequently ill because they eat large amounts of sugars and fats. These foods do not have the proper vitamins, minerals and nutr

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ients that the body needs to function properly.

Eating disorders are also very dangerous to your health because they increase the risk of many chronic d

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

iseases and conditions. The more overweight you are, the more your risk increases for diabetes, heart disease, high blood pressure, and certain types of

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

cancer.

If you suspect you suffer from binge eating disorder, it is vital that you know you are not alone. Some people who have the disorder are success

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ful in controlling it themselves and some are not. Never be afraid to seek professional help. Most people do well in treatment and overcome binge eating.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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