E-Articles - Health and Fitness

With more an more people turning to healthy eating there is always going to be those that go to extremes. Women despe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rately trying to look good by losing weight are always at risk of developing Anorexia Nervosa through excessive dieti

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ng. Women aren't the only sex at risk as more and more men are developing Anorexia Nervosa too.

Anorexics see themse

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

lves as obese no matter how much they weigh or how thin they look in the mirror. Sadly, they can't see themselves as

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nything other and refuse to seek help or accept it when offered, and simply diet until, for 10 to 20 percent of Anore

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

xia Nervosa suffers they eventually die from related complications.

Most sufferers are often perfectionists that can

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

be very strict with themselves and set high and unrealistic goals that will not lead to anything other than failure.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Often what leads to this behaviour is a lack of control in some other part of their life. They realize that they can

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

gain some control back or the power they feel from being in control of at least one part of their life, by dieting. T

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

his slowly turns into an obsession as they self monitor their food intake and their weight, as they gain satisfaction

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

from finally being in control of something.

This obsession or focus on constant monitoring of calories and weighing

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

themselves helps them block out unwanted feelings and emotions. So it can be seen as a symptom of possible mental he

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

lth problems, especially around self-esteem or what I prefer to refer to as self-acceptance. This need for control do

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

esn't help them as they live in denial and refuse to seek help basically because they don't feel they deserve the att

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ention and most feel they don't deserve to eat: this tying into problems with self-acceptance.

However bleak the pic

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ture painted in this article so far, remember that the majority of Anorexia Nervosa suffers do not succumb to the ill

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ess and help is at hand for all. There are a number of treatments available to sufferers. Medical care especially for

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

those with severe anorexia is available along with psychotherapy. Cognitive Behaviour Therapy (CBT) is proving very

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

affective in tackling helpful thoughts and behaviour that are at the core of the eating disorder. Recognizing trigger

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s and developing coping strategies that patients can use to help take control of their anorexia can be very effective

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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