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Anorexia is a very common neuropsychological disorder that has a very high incidence in the young population. Anorexia is not just an eating disorder, it also involves m

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

any addictive behaviors and the development of various phobias related to food and being fat. Anorexics develop inaccurate perceptions of their physical appearance and t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ey often see themselves as fat, regardless of how much they actually weigh. Anorexia is a very complex disorder caused by multiple interrelated factors. Although in the

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ast anorexia was thought to be a purely physiological disorder, recent studies have revealed that it occurs on the premises of neuropsychological dysfunctions. Certain e

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

vironmental factors also play a major role in the development of anorexia and the disorder seems to occur due to poor adaptation to the requirements and the ideals impos

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

d by the society.

In many cases, anorexia is developed by teenagers who come from very restrictive, demanding families. Children raised in a cold, insecure, non-functio

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nal familial environment are very exposed to developing anorexia. Young people who originate from dysfunctional families often suffer from depression, emotional insecuri

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

y and low self-esteem, features that can facilitate the development of anorexia or other types of eating disorders.

Despite its pronounced environmental valences, anore

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ia is not entirely a psychologically-induced disorder. Medical scientists also suspect certain genetic factors to contribute in the occurrence of anorexia. Various studi

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s have revealed that most patients have a family history of the disorder, suggesting a pronounced hereditary character of anorexia. Scientists believe that the genetic p

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

edispositions to this type of disorder can be easily transmitted from one generation to another. Hence, people who have blood relatives with anorexia are also at risk of

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

developing the disorder.

Although anorexia can occur in both sexes, the disorder has the highest incidence in the female gender. Anorexia is very common in adolescents

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

but it can also affect very young children or adults. Despite the fact that the disorder can occur in virtually any ethnical group and culture, anorexia is a common pro

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lem in Western society. The high prevalence of anorexia among people who belong to well-developed socioeconomic groups confirms the pronounced influence of environmental

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

factors in the development of the disorder. The excessively promoted topical ideals of beauty and the pressure exercised by modern society upon the young have a great co

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tribution in the occurrence of the disorder in teenagers.

The categories of people exposed to the highest risk of developing anorexia are: teenagers, athletes, people w

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ith carriers that require maintaining a slim body (models, actors, dancers), people with a family history of the disorder, people who come from dysfunctional families an

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

people with emotional problems (low-self esteem). Overweight children and teenagers are also very exposed to developing anorexia. People who suffer from anorexia may in

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

time also develop bulimia, a similar type of eating disorder.

People who suffer from anorexia need a lot of help and support in order to overcome their condition. Altho

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

gh people with eating disorders need to show a lot of ambition and cooperation in the process, anorexia can be effectively overcome with the means of psychiatric therapy

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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