E-Articles - Health and Fitness

With summertime activities getting into swing, many people are spending time outside planting, weeding, and t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ending to their gardens. Even though gardening is a chore for some and a hobby for others, it also provides a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

n intense workout, using all of the body’s major muscle groups. It is important to prepare joints and muscles

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

prior to gardening to protect your back from all the bending, twisting, reaching and pulling it entails. Like

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

any exercise, gardening requires proper warm-up and technique to avoid injury. The simplest warm-up is walki

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

g. This should be followed by some flexibility exercises. When doing the following stretches, do not bounce,

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

and only go as far as you comfortably can. While standing, prop one heel up on a stool or step. Keeping your

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

knee straight, lean forward aiming your chest toward your toes. You should feel a stretch in the back of the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

thigh (hamstring). Hold for 30 seconds, the repeat on the other side.

Stand up, balance yourself, and grab o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e ankle from behind. Pull your heel toward your buttocks, and hold for 30 seconds. You should feel a stretch

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

in the front of the thigh, or quadriceps muscle. Repeat with the other leg.

While standing, clasp your hands

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

above your head. Lean to one side and hold for 30 seconds. Repeat on the other side. Proper form w

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ll also help you avoid injuries:

• Use long-handled tools to avoid forward and sideways ben

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ding.
• Switch hands frequently when raking or hoeing.
• Bend from the knees, not the back, when pi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

king up yard waste or emptying the grass catcher. • Keep overhead work limited to five minute episodes.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

• Carry medium to small- sized loads close to your body, or use a wheel barrow or wagon to avoid back strain

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

• Save heavier work for midway through your chores so you are more warmed up.
• Use knee pads whe

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n kneeling.
• Kneel down instead of bending over for prolonged periods.
• As with all exercise, dr

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nk a lot of water to prevent dehydration.

Gardening properly and safely will help you grow stronger. You can

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

burn up to 300 calories per hour. Using the above tips will make your gardening more enjoyable and pain free

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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