E-Articles - Health and Fitness

1) Carpal Tunnel is actually a rare condition affecting only the wrist area. If you have pain in any area other than your wrist, such as

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

your neck, lower back, arms, etc. you probably have RSI (Repetitive Strain Injury). RSI causes symptoms characteristic of Carpal Tunnel

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

, but it involves your entire upper body.

2) Carpal Tunnel surgery is not an effective treatment for RSI. Because the muscles you use w

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

en working on the computer are very small, extensive computer use can cause these muscles to become inflamed. This can aggravate surroun

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ding nerves, cause pain in restricted areas (such as the carpal tunnel), eventually scarring the tissue. This damage is cumulative.

3)

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

You can improve your condition drastically by changing your habits. How many people do you know who stretch and warm up the muscles cont

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

olling their fingers before working them? A professional athlete would never consider competing without warming up and stretching. If y

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ou use the computer more than two hours per day, you need to condition your upper body regularly like an athlete.

4) Repetitive Strain

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Injury is a result of a particular lifestyle—one that only you have the power to change! I first learned of RSI when I went to work for

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

fortune 500 company as a sales person three and a half years ago. I was working more than ten hours per day at a high-stress job, spend

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ing the majority of my day on the phone and computer. By the end of the day I was exhausted from the stress and had no energy left to ex

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ercise. Soon, I began waking up many mornings with a painful stiff neck that would last for weeks. The pain in my left elbow would keep

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e awake at night. My entire life was affected; my moods, my activities, and it spilled over into my relationships.

5) Soft Tissue Treat

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ment can be an effective alternative to surgery. I began to research my condition, feeling sure that there must be a less invasive, more

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

effective treatment for my RSI. My sister had been bedridden with back pain a few years ago, and her wrist pain was so severe that she

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ould no longer function at her job. Finally, through regular treatment by a soft-tissue specialist, including a regular stretching progr

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

am, she has become pain free, has returned to programming, and can carry her toddler with ease.

Time crunches make us all forget to tak

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e regular breaks, and we end up getting less exercise than we need in general. The key is to take charge of your own health care, and be

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

confident and firm in choosing your own treatment. No one knows your body better than you do. Best of all, you have nothing to lose by t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rying non-invasive remedies before opting for surgery. So take the initiative, do your homework, and choose your own best path to health

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Are you looking for more commitment in your relationships, do you feel you're not getting the level of commitment from you partner that you're seeking? Do you want to understand why you might feel out of balance in your relationship? This article looks at the true meaning of commitment in relationships.

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