E-Articles - Health and Fitness

Following are tips for initiating a walking program for exercise:

See

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a doctor – Before initiating an exercise program, talk to your doctor and get a full ph

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ysical. The doctor will suggest an exercise program that is right for you.

Stay hy

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

drated – Especially on a hot or humid day, it is important to stay hydrated. Drink wate

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

r before, during and after your walk.

Eat well – Eat three well-balanced, moderate

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

y-sized meals per day. Avoid junk food and products with high fat and cholesterol.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

>Choose a smooth walking surface – A smooth walking surface will result in less fatigue

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

and fewer injuries.

Monitor your pace - You are walking at a good pace if you are

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

able to hold a conversation with someone.

Cease walking when there is pain – Don’

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t continue walking if you are experiencing chest pain, if you are overly tired, if you

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

eel pain, or if you experience shortness of breath. If you experience any of the follow

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ing, see a doctor immediately.

Time your walking program with your meals – Don’t w

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

alk directly after or before a meal. It is optimal to walk 2 hours after a meal and wai

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t 20 minutes after your walk before eating a meal.

Seek alternative walking areas

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

in extreme weather – It is not a good idea to walk in extremely cold weather, or brutal

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y hot or humid weather. In adverse conditions, find an indoor track to walk around or h

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ead to the mall to do some laps. Also, avoid walking on ice or during a lightening stor

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

m. If you find yourself caught in a lightning storm, head for cover (but not under a tr

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ee since lightening tends to hit the tallest objects in an area).

Follow the

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

se tips for initiating a walking program and reap the benefits of your exercise program

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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