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Pilates has been a lifesaver for me!

What is Pilates, you might ask, and just how did it save my life?

Wel

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

l, please let me tell you a story.

Pilates, pronounced puh-lah-teez, was originally developed by Joseph H.

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

Pilates, who was working as a nurse in England during World War I.

Pilates developed a series of exercises

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

that were designed to help bed bound patients to regain their strength. He connected springs to the bed mat

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

tresses and then helped the patients to either push or pull against the springs in order to create resistanc

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and to help them strengthen their muscles and improve their flexibility.

This gave the patients hope as th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ey were able to move their extremities and regain their muscle tone even though they were bed bound. What a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

gift to the world that Pilates created and then refined over the years has been such a blessing to so many!

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

After having been unable to lose the baby weight after the birth of my last child and as my knees and hips

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

have gotten more achy as I have reached 40, I was looking for a more gentle exercise that would still give

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e a good workout and hopefully give me the healthy body that I used to own.

Pilates helped me to do that wi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

thin just a few weeks. Since Pilates focuses so much on training the core muscles of the body, my abdominal

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

muscles as well as my back got a great work out early on. I also found that the gentle movements of Pilate

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s helped me to have fewer aches and pains in my legs and backs, especially after I have worked a long shift

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

on my feet.

Pilates is an incredibly easy and gentle exercise that is so powerful!

It helps you to strengt

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

en and lengthen your muscles. Pilates allows you to become more flexible. I feel better.

I have more flex

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ibility than I have had in years. My back doesn’t hurt so much any more and for the first time in my life,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Pilates has helped me to find some abdominal muscles! Who knew they were there!

Pilates is an incredibly m

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

otivating exercise since I have been able to see the results of the magic Joseph H. Pilates created so long

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ago.

So, if you haven’t tried it before, take a Pilates class and give this exciting form of exercise a try

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Truly this spiritual journey is the adventure of a lifetime! It's a daily quest for God's Kingdom and righteousness, living and learning, so help us God.

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