E-Articles - Health and Fitness

Thermogenics and "fat burners" (including ephedrine and caffeine) are effective for long term

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

fat loss.

Fat burning pills made with ephedra and other herbal stimulants have been around fo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r the past 15 years. Millions of dollars are spent on these products and are advertised heavi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ly that it makes you think you have to take them in order to lose fat.

Some of he hypes that

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ou see on advertisements in well-known magazines are:

"Proven to increase fat loss 1700%."

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

> "Burn up to 613% more fat!"
"34 times more fat lost than control group."
"5 times

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

more fat loss than exercise and diet alone."

If any of these supplements did burn fat and he

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

p you keep it off permanently than obesity would not be the problem anymore. But with all the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

fat burning supplements available today, there are now more overweight people than ever befor

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e.

Ephedrine have been pulled off the market because its ingredients are strong central nervo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

s system stimulants, they also have many potential side effects and down sides.

Be caution wh

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

en using thermogenic products especially if you are sensitive to stimulants, have a history of

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

heart disease, high blood pressure, thyroid disorder or any other medical problems. To be sa

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

fe, always check with your doctor first before using any thermogenic products.

Taking pills t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

lose fat is temporarily because is only treating symptoms. You have to address the cause of

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

the problem which is poor nutrition and lack of exercise.

There is a better, healthier way to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

lose body fat by knowing proper food choice and food combinations that are better appetite su

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

pressant than any drug or pill without the side effects.

By eating a serving of lean protein

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

such as chicken, turkey, egg whites, tuna or lean red meat with every meal, at frequent interv

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

als throughout the day, you stimulate your metabolism while decreasing hunger at the same time

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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