E-Articles - Health and Fitness

Obesity has been a deep concern in US as recent studies show that nearly one quarter of US population, pretty reluctant to avoid junk-foods, are obese and more alarming is the fact that ne

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

arly 3,00,000 people die each year for obesity. Obesity related disorders and diseases are rapidly growing up in the entire nation and a vast majority of the population is desperately sear

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ching for the methods to loose their weight and stay fit. Various training programs, diet-pills, nutritional supplements, appetite-suppressant, Green Tea Extract Supplements, or even Algae

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

Tablets have covered the market as a whole to meet up the needs of the growing obese population. Each product has its own claim, like - "Reduce 20 lb in a month - Guaranteed", or "Reduce

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

10 lb in a week - Guaranteed", which have mostly been identified as fraudulent claims and despite FDA, being pro-active to detect such exaggerated claims, it is hard to give it a check bec

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ause of the demands. People are just getting crazy to loose those extra pounds.

Quite often than not, most of the weight loss methods involve a crash-dieting: getting into a quite unnatur

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

al food habits, a diet which is totally fat free; it contains a bare minimum amount of carbohydrates and proteins; in some intense diet chart - there is only provision for salads, fruits o

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r custards; some diet chart includes only water and liquid/juice. Though you may look slim and thin after adapting to a crash dieting at the initial stage, but if continued over a period o

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

f time, you cannot avoid the risk of a long-term damage.

This is simply another form of starvation, a self-starvation, which may eventually lead to fatal consequences. As food provides th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e necessary energy to our body-cells to undertake much needed metabolic activities, absence of food will simply mean that you are not supplying energy to your body, so it is quite natural

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

for your body to stop metabolic activities gradually, such a disorder is termed as anorexia, a direct consequence of crash dieting. In its advance stage, you may have breathing trouble, lo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

w blood pressure, or even a heart failure; this is particularly dangerous for the pregnant women as they may run the risk of miscarriage. Anorexia may even lead to osteoporosis.

Thus a st

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eep crash dieting is not the best option available for your to reduce the extra pounds, and it is better to take a low calorie diet with some regular exercise to reduce those unwanted fat

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

from your body. If you are not quite sure about the exercises or the diet charts, you can obviously go on for trying the weight loss video training programs available today, which focuses

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

mostly on reducing your fat, and at the same time keeping you healthy and fit. It is often quite confusing to decide which program to choose from amongst a handful of available options. As

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a general rule of thumb, in the beginning you should avoid programs that are loaded with difficult exercises. It is always better to start with simple but challenging exercises as this wi

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ll develop your confidence level and at the same time contribute towards the desired result. The programs should communicate in detail every move and steps and should be instructive in nat

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ure. A lot of repetition of catch phrase, as found in few such programs, may eventually spoil your mood. The video should be interesting to watch, as you need to watch it over and over aga

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

in to follow the instructions and the exercises exactly.

Thus, to burn those extra calories in order to perfectly shape your body, a crash dieting, or diet pills, or anything - that claim

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s to give overnight or quick effect - is not the best practice. It is better to have some routine work out and to take low calorie foods only as per the advice of the experts in this field

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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