E-Articles - Health and Fitness

As an addendum to my website on positive relaxation, I felt it important to write briefly about some specific, simple methods that anyone can app

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ly to help them relax.

We live in a stressful world- there are appointments to keep, traffic to get through, deadlines, meetings, home duties, a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nd so on.

The list can be long, and for some, just reading the list can be stressful.

Let us take a moment to see if we can put all the above i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

to perspective.

Often, the way we see things, or our attitude can make all the difference.

I, like many people, have a very busy life, but I ha

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ve made a point of practicing several techniques, that do take time, but the dividends are paid back many times over in my healthy zest for life,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and more relaxed outlook. This in turn, has allowed me to be more productive too.

One of the things I do is wake up a little earlier each day, i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t need only be 15 minutes, and meditate.

This can be a very straight forward process- simply closing your eyes, and thinking about as little as

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ossible. We often have so much going through our minds, that we miss the opportunity for stillness. By thinking about as little as possible, (

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and if necessary, to do this, start to think of a calm, tranquil place, and then drift from there to nothing). I understand this can be difficul

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

at first, but with persistence over a few weeks, the difference will be immense.

Another option is to practice yoga. For all of you whom may t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

hink this is way to hard, there are sites where yoga classes can be downloaded to an iPod, and then played back at a time of your choosing, any p

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

lace you wish.

I have found that the benefits of yoga are immense, where my mind is able to be harmonised, and placed at peace, and I’ll typical

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y feel very refreshed after a session.

I truly recommend this option, for the more adventurous of you. Once yoga is tried, it can be addictive,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

where you may look forward to the benefits, where you will feel refreshed, happier (due to the endorphins released when the body is exercised), a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d more at peace, both mentally, and physically.

Another option, typically at the end of the day, is to take a hot bath or shower- this will be b

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

oth cleansing, as well as relaxing for you physically, and will often be a perfect pre curser to either a good night’s rest, or a session of guid

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d imagery.

Guided imagery is a different way to relax, where you are lead by a soundtrack that guides you through a relaxation state, and can be

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

pre purchased or, even recorded by yourself.

Yes, I realise the above all take effort, but anything with value would. It may even seem unreas

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nable, at first to even consider the extra work in our busy life, but please believe me on this one- the effort is very well worth it.

I write r

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

egularly about relaxation, as it is a passion of mine, and I feel, a need more than ever, in our busy world, to practice.

Be the best you can be

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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