E-Articles - Health and Fitness

Our society loves the quick fix. We embrace the get it yesterday approach to all walks of life. When it comes to our health we will go to great lengths t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

o achieve our goals quickly and as effortlessly as we can get there. What if there was a better way?

When it comes to aerobic exercises walking is by far

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

the safest approach, period. Walking will help you strengthen your bones, condition your heart and lungs and help control your weight. Being consistent in

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

your walking exercise routine is one of the most important factors in developing a healthy physical activity program. Research has shown that people who w

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

alk approximately 20-25 miles per week outlive those who don't walk by many years. Twenty miles a week sound tough? How would you like to break it down?

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Let’s see, an average person can walk about 3 miles in an hour. In 30 minutes that would mean about 1.5 miles give or take. So if we are looking at a 7 d

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ay week and a 30 minute investment per day then we are looking at a total 10.5 miles per week. By just going the full hour once a day, take the dog with y

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

u, then you will get to 21 miles per week. Folks, it can’t get any easier than that and the reduced stress factor from this is invaluable to your overall

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

health and well being.

The following are some quick facts about walking:

On average, every single minute walking can extend your life by 1.5 to 2

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

minutes. How’s that for pay back?

Walking an extra 20 minutes each day will burn off 7 pounds of body fat per year.

Still want that piece of candy you h

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ave been eyeing all day? You would need to walk the full length of a soccer pitch to shed that desire.

The longer, moderately-paced daily walks (30 minut

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

es at about 70% maximum heart rate) are best for losing weight.

Just looking to condition your lungs or improve on your overall heart muscle? Shorter, fas

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ter walks (20-25 minutes at up to 85% maximum heart rate) are best. Walking will also provide the following benefits:

Improves efficiency of your heart a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nd lungs

Burns body fat

Raises your metabolism so you are burning calories faster, even while you rest

Increases your energy

Reduces levels of choleste

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ol in your blood

Lowers high blood pressure

Helps control and prevent diabetes

Reduces risk of some forms of cancer including colorectal, prostrate, and

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

breast

Promotes intestinal regularity

Helps promote restful sleep

Strengthens muscles of your legs, hips, and torso

Strengthens your bones and reduces

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

bone density loss in older women

Reduces stiffness in your joints due to inactivity or arthritis

Walking is much more preferable than running or jogging

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

because it creates less stress on your joints, including hips, knees, and ankles. Remember to properly warm up before and cool down after every walking se

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ssion...your muscles will love you for it! So what are we waiting for? Get to twenty miles a week and then see where it takes you. Think of the joy of go

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ing to Nordstrom’s and having to buy all those new clothes and for the right reasons for a change. Take a step in the right direction and do it by walking

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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