E-Articles - Health and Fitness

Elliptical trainers are not only good for keeping fit but they can also aid you in recovering from a sports i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

njury. Recently while playing racket ball I sprained my knee and pulled one of my quads. I used the ice packs

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

to get the swelling down but the stiffness started to be a problem. I needed to loosen things up but everythi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ng I was attempting resulted pain or discomfort. After about a week rest I got on my elliptical trainer and s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

owly began to work my knee and sore muscle groups.

I took it easy and only did a very slow 15 minute workout

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

. Elliptical trainers are known for their ability to provide a total body workout without impacting joints, b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nes and muscle. This became very apparent as over the next several days I slowly began to get strength and fl

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

exibility back into my knee. I kept the workout sessions to less than twenty minutes. I also applied ice pack

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

after each work out to control swelling. It was painful walking just after my injury but surprising it was l

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ess painful using the elliptical trainer.

If you already use an elliptical trainer on a regular basis then y

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

u are most likely physically fit and your recovery most likely will be rapid when compared to sedentary indiv

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

duals. I must say that prior to using my elliptical trainer I called my friend who is an exercise physiologis

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t and Physical therapist for advice. He spent about an hour with me to assure that I was exercising correctly

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

I would strongly suggest that you also consult a medical professional that practices sports medicine before

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

jump on your elliptical trainer for a ride. Failure to do so could lead to a more serious condition or injury

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Again I think that the lack of impact to my knee during the therapy workout made all the difference. I must

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

say that I think I am recovering fairly quickly. I think in about two weeks I may even be able to do some ro

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d work. I probably will hold off on that to reduce the risk of a reinjury. The elliptical trainer will provid

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e just about the same fitness benefit while protecting my joints. I do miss my racket ball with friends but t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

at will have to wait until next month. I am just glad that I have my elliptical machine to help me to recover

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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