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E-Articles - The Need For Exercise
Prior to the 70s, our parents and grandparents led physically
active lives. They did this without having to go to the gym, or
having to participate in formalized exercise programs. Our
parents and
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
grandparents were able to accomplish this because
they walked a lot more than we do today, and they did not have
the many household labor-saving gadgets that we now have.
Strength and stamina wer
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
the mainstays of that era.
Exercise is necessary these days because household labor-saving devices have reduced or eliminated manual effort. When I was growing up my mother washed our clothes in t
Exercise is necessary these days because household labor-saving devices have reduced or eliminated manual effort. When I was growing up my mother washed our clothes in t
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
he bathtub on a scrub
board. We didn’t have an electric washing machine. Needless to
say we didn’t have a dryer either. My mother had to lug those
heavy wet clothes up a flight of stairs to the ro
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
f.
We opened tin cans with a good old-fashioned can opener. That was really great for the arms. There were no “pop” tops back then. Remember the automobile before electric windows were installed in
We opened tin cans with a good old-fashioned can opener. That was really great for the arms. There were no “pop” tops back then. Remember the automobile before electric windows were installed in
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
them? We exercised our arms another way—by cranking the windows
up and down.
Before gasoline-powered snow blowers and lawn mowers, we shoveled snow and pushed mechanical mowers through grass and
Before gasoline-powered snow blowers and lawn mowers, we shoveled snow and pushed mechanical mowers through grass and
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
weed. Our
parents and grandparents were a lot fitter than today’s
generation because they didn’t have these machines.
There is nothing wrong with technological inventions. They save a lot of time
There is nothing wrong with technological inventions. They save a lot of time
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
and remove drudgery from household chores. But we do
need to replace the fitness-generating activities that these
machines eliminated, with exercise.
They call these machines 'labor-saving' for a
They call these machines 'labor-saving' for a
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
eason. The
result of their saving you physical labor is more time at your
disposal. That time should be used to implement a good exercise
program.
An unfit body is just like a car that has never
An unfit body is just like a car that has never
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
been
given a tune up. It becomes less efficient, less reliable, and in
the long run will wear out faster and cost more to repair.
A fit and healthy body will reward you handsomely. You will wake
A fit and healthy body will reward you handsomely. You will wake
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
p in the morning ready, willing, and able to tackle any problem
you encounter. You will be better able to handle stress, and not
have it cause a physical problem. You will not believe how great
yo
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
u will feel. There will be no aches or pains. Your muscles will
be toned and primed—ready to move mountains if need be (I
exaggerate but you get the point).
One hour of exercise yields two hours of
One hour of exercise yields two hours of
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
longevity. Exercise
prevents muscle wasting as you age and stops bone loss which can
result in osteoporosis. It stabilizes blood sugar, lowers blood
pressure and improves blood and oxygen flow thr
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
oughout the body.
According to studies, increased oxygen flow to the brain has the
effect of improving memory and learning.
I am experiencing the benefits of exercise right now. My body is fit an
I am experiencing the benefits of exercise right now. My body is fit an
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
healthy. It is fit from exercise and healthy from eating
nutritious, heart-healthy meals. Most people don’t know what it
is to have a properly functioning body. They are under the wrong
impressio
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
n that as one gets older, the body is supposed to become
fragile, and subject to all manner of ailments. Nothing could be
further from the truth. Implementing an exercise plan and a
little common
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ense will prevent that from occurring, or at least
slow it down considerably.
Having an unhealthy body because of advancing years does not have to be inevitable. Society leads you to believe that s
Having an unhealthy body because of advancing years does not have to be inevitable. Society leads you to believe that s
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
enior
citizens should expect to have multiple debilitating illnesses
and wind up in a nursing home, or in someone’s care. I don’t
subscribe to that old wives’ tale, and you shouldn’t either.
A co
A co
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
sistent exercise program is not a luxury, but a necessity.
Our technologically advanced society is causing more stress, and
is rendering an active lifestyle more and more unnecessary. The
world’s
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
burgeoning obesity epidemic is to a large part a
testament to that. There is no magic pill that will fix this ever
worsening situation. A decision has to be made on an individual
basis to exercise
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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