E-Articles - Health and Fitness

Stretching is just one piece of the workout puzzle that helps athletes to achieve peak performance. But, done in the wrong way at the wrong

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

time with the wrong methods and you actually do more harm than good.

So if there is such potential for problems why would you stretch?

To m

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ove our skeletal system around we have muscles attached to bones. Muscles do one thing – they contract. That is how they work. All action

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s due to muscle contraction. If muscles only contract they then become tighter and tighter making the opposite movement more difficult.

Tak

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e your arm as an example. To bend your arm at the elbow your bicep muscle contracts. To straighten the arm your tricep muscle contracts, pa

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ssively stretching the bicep muscle.

Now, to be stronger muscles need more contractile strength. To get more contractile strength they must

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

get longer. Therein lies a reason to stretch.

Stretching also gives a joint more extension when moving. You must be careful not to allow t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

he joint to become too flexible however. Stretching helps to prevent injuries because the muscles are longer and the joints more flexible.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Stretching also promotes faster recovery from intense workouts since it helps to remove toxins and waste products from the muscles. It promo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

es better posture and balance, improves your coordination and circulation. Stretching relaxes the body, reduces stress and just feels good!

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

There are also specific rules to stretching that will prevent injury and enhance your performance. There are two types of stretching that b

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

enefit athletes: static and proprioceptive neuromuscular facilitation (PNF). PNF is best left to those who are familiar with the techniques

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd can be spotted by a professional when first learning.

Static stretching is most often used. Basic rules include no bouncing since it str

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

esses the muscles and tendons. It is started by slowly moving the joint to it’s end range of motion. You’ll feel a gentle pulling. Hold th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

at position for 20-30 seconds and then release. Do not stretch to the point of pain because you’ll cause injury to the muscles. A set of 3-

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

stretches done on one muscle group is sufficient to gain the benefits. Stretch one muscle group and then the opposing group. For example s

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tretch the bicep muscle and then the tricep muscles.

Stretching should always be done separate from your workout or at the very least, after

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a workout. Your muscles should be warmed but stretching before a workout can actually hinder your performance.

The benefits of stretching

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ar outweigh the potential problems, especially when done correctly and after your workout. You’ll find you are less stressed, have better mo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

bility, posture, circulation and recover faster from intense workouts. Stretching can improve your performance and even help you sleep better

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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