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Had a few great training sessions this week, and here is this week's best t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

raining tip that I want to share with you.

Always Use Non-competing Supers

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ets in Your Workouts

As you may know, I only use supersets of non-competin

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

g exercises in my training programs. That means that the two exercises in t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he superset must not interfere with one another. For example, the first exe

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

cise, let's say a dumbbell press, must not interfere with the second exerci

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

se, say a dumbbell row. That's a nice little upper body superset right ther

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e.

One of the tough things about designing the perfect non-competing super

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

set is to avoid fatiguing your grip. For example, pairing a Dumbbell Row an

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

d a Dumbell Split Squat are perfect in theory (because you are training upp

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r body and lower body), but both exercises demand a lot from your grip. So

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

it would make for an ineffective superset (both exercises would fail in gri

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

p first, before the back or leg muscles fatigued).

On Thursday I did a sup

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

erset of exercises that I had never done before: Barbell squats and wide-gr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ip seated rows. It was a great combination with absolutely no competition b

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tween muscle groups or grip - so I could work very heavy in both exercises

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

- therefore leading to the most "turbulence" on my body - and therefore, th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e best training results.

An alternative bodyweight version of that superse

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t would be Pistols supersetted with Pullups - talk about a tough, functiona

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

l superset. Even the world's strongest man would have a tough go with those

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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