E-Articles - Health and Fitness

Yes, it's true. These two standard ab exercises, crunches and situps, can actually

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

be murder on your low back.

Why? Because they involve spinal flexion (rounding y

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ur lower back to allow you to bend forward at the waist). But according to researc

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

h, that's the exact mechanism that causes a herniated disc in your lower back. Aft

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

r all, most people "throw their back out" bending over to pick something off the g

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

round.

So it makes sense to limit the amount of traditional sit-ups and crunches

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n your program. Plus, you can't spot reduce the fat from one area, so you are bett

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

er off spending that exercise time on a better total body exercise or intervals. I

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

you want to flatten your abs, you need to lose body fat.

So to improve your abs,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

use the following techniques:

1) Take half the time you were spending on abs, an

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

do intervals with that time instead.

2) Spend the rest of your ab training time

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

doing endurance ab exercises, such as planks, side planks, mountain climbers, and

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ariations of these exercises.

3) Keep your abs braced in all exercises so that yo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

u work your abs in every movement that you do.

For advanced bodybuilding, there w

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ll come a time that you will need to do traditional crunching motions. But it is b

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

est, for results (i.e. growing your abs) to do these with resistance. Cable crunch

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s are good, and you can get results with a relatively small amount of spinal flexi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

on.

But really, when it comes to having great abs, losing body fat is the most im

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ortant aspect for most people. And if you are a desk jockey, its more important fo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

r you to have abdominal endurance than to risk your back with classic ab exercises

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - Why Crunches & Situps Are Bad for Your Back

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