E-Articles - Health and Fitness

Do you find exercise to be a chore? Does it seem to be difficult to keep it up? Many people start with great intentions and are determined to start off with a fitness program that is going to change their lives/health/fitness ov

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ernight. It doesn't happen. You know the pattern - start full of enthusiasm and then day by day the regime gets a little shorter, the effort to keep going seems harder to find.

Don't worry, everyone has exactly the same problem

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

. We all go through just the same thing. All the exercise guru's and fitness trainers stand there and tell you how great you are going to feel and how they are going to change your life. Then things fade off and a few months dow

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the line you are still sitting on the couch wishing that you were like the guys you are watching on the TV.

OK. Lets try and address what’s going on here. First off, don't believe that you are alone. The vast majority of peopl

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e are in the same boat and have exactly the same problems. So, you want to be healthier and feel fitter, more vibrant and generally get that energy boost that everyone seems to go on about. Does it all sound like too much effort

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

I would advise that first you ensure that you are getting all the vitamins and minerals that your body needs. If you are short of anything in the nutritional sense then you will not feel like doing anything much. You will lack

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

energy and not get around to even feeling like exercising. Ensure your diet includes the basic '5 a day' fruit and veg, or if not take supplements. A good multivitamin daily is good. Get one that includes iron - needed for the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ed blood cells. You won't feel like doing anything much if you are in any way anaemic. Also vitamin b complex is good to take regularly. A brewers yeast tablet daily will supply the vitamin b's. Extra energy can be attained by u

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

sing other supplements such as Ginseng - an ancient Chinese remedy which is gaining in popularity in the Western world.

Making sure you are well balanced from the inside will help to give you a feeling of well-being which in tu

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n will make you feel more like keeping up with a fitness program. Eat regularly, little but often, and drink plenty of water. Limit the alcohol! Right, enough of the lecturing. How can we get the body exercising?

Fitness comes

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

from exercising the body. Its as simple as that.

Next fact; people are lazy. They don't like exercising. Sitting on a couch is easier. Doing nothing is the simplest path. Now here is the major point of all this. The way your bo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

dy is built is that it will follow the easy route and settle into the easy way, unless convinced otherwise. Once it starts getting regular exercise it will actually begin to crave more! Your body will ask you for more exercise w

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

en it starts to feel better - it maybe a strange way to think but this is important. Listen to your own body. Give it a little teaser. Take it for a walk each night. Just half a mile down the road and back. After week give it a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

little extra, a brisker walk and a longer distance.

A week later, your body is saying to you that it wants a little more. You will feel like helping it. Go on, indulge it, try getting on that stepping machine. A short time a da

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

. Turn on the TV and do it when watching your regular programs. The main thing to remember is that even after a little exercise, you body will start to ask you for more. Go along with it.

Make sure that you use different exerci

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

se machines, to add variation and interest. You've probably got them all - exercise bike, elliptical cross trainer, weights, rowing machine. All the things you have seen and bought before and not used. Well dust them off, and us

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

them while you are watching your TV or DVD's, it keeps your mind occupied while you are exercising and stops you getting bored.

Above all else, make it interesting. Use any means you can. Music, DVD's, TV, audio cassettes, it

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

doesn’t matter. Plug your iPod or MP3 in. Get two machines and compete with your partner - make it a race! Or just compare distance/repetitions as recorded on the digital readouts. Do some exercise on one machine and then jump o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to another. Keep changing - make a mental game of it - imagine you in a Decathlon. Don't stick to one machine. Keep changing, keep interested. Boredom is the killer in this - don't give it a chance!

So, the most important fact

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to digest is the one that says your body will not only accept exercise but will actually ask you for more. Start it off and your own body will beg for more. Once started this is self generating! You just have to go along with it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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