E-Articles - Health and Fitness

Although any physical activity is beneficial to your health, variety is an importan

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t component to getting maximum results from your fitness program.

Our bodies are c

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

onstantly adapting to the physical stresses placed upon them– figuring out the most

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

efficient way to perform an action. If you follow a regular strength training rout

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ine, your body will adapt to that program in approximately 4-6 weeks. Although you

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

will still benefit from doing that program, changing to a new group of exercises wi

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ll challenge your muscles in new ways, resulting in better results.

Adaptation als

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

o takes place with cardiovascular exercise. Runners who follow the same course eve

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ry run would get more effective workouts by using different routes. Cross training

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

is also a great way to add variety to your aerobic workouts. If you’re a regular

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

alker, you might try swimming, cross-country skiing, dancing, or biking for a chang

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e. Those of you who go to the gym and always use the same cardio machine, on the s

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ame program, for the same amount of time at the same intensity would do much better

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to mix it up. Use different equipment on different days or even alternate machine

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s within one cardio workout. Varying machine can also help you avoid repetitive st

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ess injuries.

Besides physical boredom, another important reason to spice up your

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

fitness regimen is to avoid mental boredom. Studies have shown that people who rou

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tinely change their workout programs are more likely to exercise regularly. Yes, i

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nitially, it may take a little more thought and a little more time to learn a new a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ctivity or a new strength training program but the benefits are definitely worth it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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