E-Articles - Health and Fitness

Dear DM,

To be honest, my body is pretty ok, but I'm suffering around the butt area and was just wondering what is

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

the most effective form of cardio to get rid of it? Any suggestions? Thanks in advance.

Gym Goddess

He

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ho Gym Goddess!

Firstly, I totally admire you for saying that your body is 'ok' - cos in my opinion, very rarely are women today satisfied w

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ith their own physiques!

Secondly, understand that most women gain weight and store bodyfat easily in their hips, thighs and butt. Which is

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lso why there's no surprise you almost always see the women hogging the machines that target these areas at the gym (the next time you step i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to your gym.. just see for yourself). So it's no surprise to me also, that you, just like most other women, ask this question again and again

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

.

Okay, on to the issue now. Firstly, know that it's not possible to spot reduce any 'problem' areas in your body. Spot-reducing has

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

always been, and always will be a myth!

Those silly ads you see on late night television with those Ab & Butt machines from the fut

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

re all make it seem as if you CAN spot reduce (plus, they also don't tell you that those people with spectacular physiques on their machines

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

are mostly professional Fitness Models, and DID NOT GET THAT WAY spending all their time on a funky machine that can be folded and tucked awa

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

underneath your bed!).

Then again.. you could cardio from now to doomsday and maybe lose it in all the other places BUT your butt. You can'

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

target a certain part of your body to lose weight, but only target tone/weight train your muscles. However, adding in some lower body exerci

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ses with weights would enhance and do more to 'firm up' that area with some muscle, rather than relying on the stepper or eliptical machines

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lone. For the butt, you could shift your weight training focus to:

1. Squats
2. Lunges
3. Hip Extensions
4. Biking (A station

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ry bike)

The bottom line, in order for you to look good from behind - is that you need to do weight train those areas AND engage in any type

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

of cardio. For accelerated weightloss, I'd suggest a minimum of 4 cardio sessions per week, and every session needs to be a MINIMUM of 40 mi

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

utes, at one go. (I've got a friend who broke up his cardio sessions into shorter 15-minute sessions and wondered why he wasnt reaping the fu

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

l benefits of cardio). Also, don't forget to cut down your food intake a little, and be wary of what you put into your mouth.

On a more pers

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

onal note, my current favourite machine for Cardio training is the Cardio Wave. Fitness First in Malaysia has a few of these in their gyms -

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd I think they're awesome.

Hope my advice helps. Just remember... A 'wellrounded' exercise routine will give you a 'wellrounded' posterior

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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