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Softness and eye care go hand in hand, which is only natural. No person would want to put anything but the softest, smoothest contacts against the surface of the tender and delicate eyes.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

Contact lenses used to all be made of rigid glass, and over time, users reported frequent problems associated with these original types of lenses. Sometimes they would shift, causing sc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

atches on the cornea. Sometimes they would trap dust, lint, sand, or other air born foreign agents, and if these got up under the surface of the contacts, it could lead to serious irritat

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

on or actual damage to the eye. Soft contact lenses came about as a result of decades of extensive research into the problem with more rigid glass lenses.

Soft contact lenses are made of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

a special material that is not only very smooth, but it also retains moisture very well, allowing the surface of the lenses to stay wet, so that they don't abrase the surface of the eye.

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ot only do they stay moist over extended periods of wear, but they are also designed to resist protein film, which builds up on the surface of contact lenses as a natural occurence, becau

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e our eyes have filmy proteins in them. Normally this protein does not in any way interfere with crisp, vivid vision, but when the eyes have contacts in them, the contact lenses tend to a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

cumulate this protein substance and it remains deposited on the lens, like a film or gummy substance. This can impede vision, just as having film on our regular eyeglasses can make them h

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rd to see out of. So the better engineered soft lenses are made to resist this kind of build up of film, and that means you don't have to be as concerned about constantly removing and rin

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ing them off to keep your vision sharp.

The material used to make soft contact lenses is also permeable, which means that it lets a free flow of oxygen occur. It may not seem like the ey

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

s need to breathe, but they do, and good contacts are designed to allow air to pass through them, keeping the eyes oxygenated and healthy, unlike the old glass lenses used to do, that wou

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d not let the eyes properly get their fair share of fresh air.

Soft contact lenses are available anywhere you buy your contacts or eyeglasses. Just ask for them and the eye care speciali

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ts can provide you with recommendations, information, pricing, and color guides, if you would like to purchase soft lenses that have tinted hues to them, for cosmetic refreshment and fun.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

As with any eye care product, be sure to buy them from a reputable source, and make sure you go regularly to your eye doctor to have your vision and prescription strength checked and, if

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

eeded, adjusted to keep up with development of your eyes and your vision. Even if you wear bifocals or the new types of contact lenses that have two separate kinds of light refracting pre

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

criptions embedded within them, you will be happy to know that there is a wide variety of contact lenses to suit your needs, available in the soft and silky materials used to create the e

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

er increasing inventory of soft lenses for those who are tired of red, sore, irritated eyes that require constant irrigation.

Soft contact lenses come in all types, and they are many var

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

eties made for extended wear or convenient disposal. Try them in blue, green hazel, tiger eye, cat eye, leopard spots, stripes, pinwheel designs, or customized logo patterns. If you want

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

o get samples of soft lenses and experiment with how they look and feel, just visit the eye care centers in your community, or on the worldwide web, and ask for packages of free samples,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

hich most dealers are more than happy to provide to you so that you can see for yourself - no pun intended - the comfort and crisp vision that soft, silky, always moist contacts can offer

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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