E-Articles - Health and Fitness

It is well known that the consumption of vitamins can contribute to a healthy body and lifestyle although most people are not aware th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

at vitamins and minerals are also necessary to maintain vision health. The cells in the body, eyes included, are dependant on the typ

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e of diet and environment that they are exposed to. A poor diet will lead to cell reconstruction becoming below par which in turn can

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

result in diseases. Our diet can dictate how our cells restructure and a diet full of nutritious foods can ensure that our cells are

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

constantly replaced with healthy cells. For the eyes, healthy cells mean good vision health.

Vitamins can be a source of prevention

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

for many ocular diseases. Cataracts can cause blindness and results from gradual clouding the eye lens. It can be prevented by the u

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

se of antioxidant vitamins C and E which can defend the eye from free radicals that injure the cells in the eye. Vitamin B or Thiamin

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

can also help vision health by maintaining the wellbeing of the optic nerve. Cataracts can also develop because of damage from ultra

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

violet light but this can also be prevented by the consumption of Carotenoids which are found in dark green, leafy vegetables such as

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

spinach. Studies have shown that the chances of age related eye diseases can be lowered by up to 25% by adding high levels of antioxi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ant vitamins such as vitamins C and E, beta-carotene and zinc to the diet. Riboflavin and Vitamin A are also excellent aids to good e

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

yesight.

Macular degeneration can also be eliminated or at least eased when enough antioxidants are consumed as caroenoids can protec

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t the eye and slow down the condition. A healthy diet full of vitamin enriched foods such as green, yellow and orange fruits and vege

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

tables is essential for vision health. Other excellent sources of necessary nutrients include blueberries, milk, poultry, eggs, beets

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and beef amongst many more. Improving the vision can be aided significantly by adding certain fruits and vegetables to the diet. In

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

creasing the daily intake of such vitamins and minerals may require the use of additional nutritional supplements. It is advisable to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

consult a professional before adding supplements to the diet while cutting down on fat, alcohol and smoking may also help as can drink

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ing enough fluids. There are many vitamin filled supplements that are designed to help improve vision on the market at the moment but

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

again it is advisable to discuss these options with a doctor beforehand.

Medical Disclaimer: This article is designed for educationa

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

l purposes only and should not be used in any other manner. This information is not intended to substitute for informed medical advice

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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