E-Articles - Health and Fitness

Although the most common cause of headaches is stress, one of the commonly overlooked causes of stress is eyestrain. In this age of computer technology, eyestrain is an ever-

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

increasing problem. Most of us over expose our eyes not only by using computers, but also by watching television, playing video games, or even reading for relaxation after a day

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

of intense computer use.

Aging Eyes

Moveover, as we age, we generally experience a loss of vision that often goes untreated. Because the loss is slight, we don’t notice

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

it or if we do, we adapt. But even if you’re only straining our eyes slightly, it can bring on headaches. Blurry vision means you’re creating too much strain on your eyes witho

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t giving them proper rest or nourishment. Remember, the tissues and blood vessels around your eyes are delicate and it’s important to treat your eyes properly. It’s also importa

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nt to keep in mind that if you wear glasses, your prescription can change over time, especially as you age. If you're experiencing headaches that seem otherwise unaccountable, i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

’s possible you need new glasses and that’s one of the first things you may want to check out.

Computer Use

If you spend a lot of time working on the computer, it’s ess

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ential you take a break for at least 2 minutes after every 60 minutes of work. The best thing to do is nothing: simply close your eyes and relax. This gives your eyes a chance t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rest and can keep a headache from developing or keep a developing headache from getting worse. When you do any work with your eyes at a close range, your eye muscles contract,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

and if you don’t take enough breaks, the prolonged use of a computer screen can result in what is now called Computer Vision Syndrome (CVS). The symptoms of CVS include blurred

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ision, strained eyes, light sensitivity, and headaches.

Helping Your Eyes

One way to help your eyes is to blink them gently but with effort a number of times whenever y

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

u think of it. This will massage your eyes and help them relax. You can also use pure rose water. A few drops of rose water in your eyes daily will help them stay moist and stre

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ss-free.

Using Sunglasses

Sunglasses are another way to protect your eyes. Sunglasses can reduce eyestrain and accompanying headaches. The pupil of the eye controls the

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

light that enters the retina. When there is only a little light, the pupil dilates to let light in. In bright light, the pupil constricts to keep light out. There are times when

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

it is so bright the pupil can’t constrict enough to keep the excess out. In such cases, we all resort to squinting. Squinting, however, strains the muscle surrounding the eyes,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

which causes fatigue and pupil constriction. Squinting easily leads directly to eyestrain and headaches. Sunglasses help because they reduce the amount of light that can reach t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

he eyes.

Using Eye Pillows

Eye pillows also keep the light away from your eyes and help with eyestrain. They are most commonly made from silk and herbs that relax tense

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

muscles and provide soothing aromatherapy. Lavender eye pillows are especially popular. Lavender has a demonstrated ability to induce relaxation and it helps in revitalizing tir

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ed eyes. It has also proven helpful in treating sinus headaches.

Treat the Problem, Not the Symptoms

Remember, once you treat eyestrain and stop creating it, eyestrain

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

eadaches will disappear. If, on the other hand, you simply take painkillers and don’t address the eyestrain, you’ll only be masking the problem while it’s actually getting worse

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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