E-Articles - Health and Fitness

Colored contact lenses were first introduced to the general public through Hollywood and televisi

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

on, but nobody in the audience realized it because it was done surreptitiously by skillful behind

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

the-scenes trickery. Actors and actresses – and their make up artists - who needed to figure out

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

a way to change their eye color safely, turned to the world of optics for the answer. Soon Audre

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Hepburn was playing the part of a blind woman, and using eye makeup – but not the ordinary kind

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

– to fool the audience into thinking she had done something drastic to her own eyes. The optical

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

llusion she created was thanks to ordinary contact lenses, with color added.

Tom Hanks, Tom Crui

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

se, Michelle Pfeiffer, Robert DeNiro, Charlize Therone, and a host of other stars have added a li

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

tle color to their theatrical performances by using colored contact lenses to enhance their chara

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

cter and make their role more vivid.

But it is no longer a trade secret reserved for movie studi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

s. Thousands of other people who are not celebrities have found themselves transformed by colored

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

contact lenses. Some choose them for costume parties but others wear them routinely, and not onl

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

to change their eye color, but perhaps just to liven it up a bit.

How is that done? Complete co

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lor change is achieved by wearing colored contact lenses with a significantly different hue or pi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ment than then natural iris. For example, you might have gray eyes but wear a pair of contacts th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

at make your eyes look hazel or green. But some people like their natural eye color and don't wan

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

to change it, they just want to make it stand out more, and they can accomplish it easily with a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

wide variety of hues and styles made specifically for the purpose of intensifying the beauty and

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

unique brilliance of eyes that are enhanced with colored contacts. Want to be the star of your mo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

vie? Ask your eye specialist to explain to you the beauty secret Audrey Hepburn learned years ago

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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