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E-Articles - A Historical Insight Into Contact Lenses
The origin of contact lens could be traced back to sixteenth century. A good number of inventors or scientists have contributed
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
to the evolution and modification of the concept behind contact lenses. So no single person could be adjudged as the sole inve
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
tor of contact lenses.
However credit for the modern form of contact lens is usually attributed to F.E.Muller. F.E.Muller's ve
However credit for the modern form of contact lens is usually attributed to F.E.Muller. F.E.Muller's ve
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
rsion came up in 1887. The other one who is also considered as one of pivotal contributor to the evolution of contact lenses is
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
Rene Descrates. Descrates invented corneal contact lens. Another British scientist John Herschel's contribution is widely ackno
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ledged.
Second half of nineteenth century witnessed a new herald in the history of contact lenses with lots of inventions and
Second half of nineteenth century witnessed a new herald in the history of contact lenses with lots of inventions and
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
innovations. That was the period in which mainstream of society got aware of the lenses that could be directly placed on cornea
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
or sclera. However this awareness was limited to only niche.
Eugen Fick's Scleral contact shells in late nineteenth century be
Eugen Fick's Scleral contact shells in late nineteenth century be
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
came an instant hit among niche. This lens was later on modified by August Miller.
With the advent of plastic scleral lenses c
With the advent of plastic scleral lenses c
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ntact lens history took a new turn and researches were diverted towards lot of sophisticated substitutes of glass contacts. Wil
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
iam Feinbloom is considered as pioneer of plastic contact lenses. One more scientist of that period Joseph Dallos earned accola
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
de for his contribution.
George Butterfield earned recognition for improved corneal lens. This is the way contact lenses under
George Butterfield earned recognition for improved corneal lens. This is the way contact lenses under
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ent the modifications.
More sophisticated and comfy lenses came on the block once Silicone hydrogel was introduced. These are
More sophisticated and comfy lenses came on the block once Silicone hydrogel was introduced. These are
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
common historical facts available on contact lenses.
This ever growing contact lens history suggests that people were actually
This ever growing contact lens history suggests that people were actually
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
in need of a better contact lens. Some historians of contact lenses suggest that it was Leonardo Da Vinci who first toyed with
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
he idea of contact lenses.
Even now innovations haven't stopped and new models of contact lenses keep coming up. Colored conta
Even now innovations haven't stopped and new models of contact lenses keep coming up. Colored conta
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ct lenses have given a different turn to the history of contact lens. With advent of colored contacts, contact lens usage is no
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
confined to only vision correction instead it could be used for fashion and fun purposes as well.
Disposable contact lenses h
Disposable contact lenses h
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
ave resulted in a great surge in popularity of contact lenses. Also the falling prices have made it possible for average users
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
o use contact lenses.
History doesn't end here. Many more innovations are impending, that are likely to come soon on the block
History doesn't end here. Many more innovations are impending, that are likely to come soon on the block
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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